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Study · Animal study (in vivo) · rat · 2000

6 results

Neurochemical characteristics of the effects of delta sleep-inducing peptide in Wistar rats with hyperactivity of the dopaminergic system.

Sergutina AV, Gershtein LM

Bulletin of experimental biology and medicine1 Nov 2000

PMID11182819 (opens in a new tab)DOI10.1023/a:1002891517101 (opens in a new tab)PepBankPUB-11182819
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In stress-resistant Wistar rats chronically treated with L-DOPA, a single DSIP injection increased monoamine oxidase activity in the caudate nucleus.

    In plain wordsIn rats given L-DOPA, one DSIP injection raised monoamine oxidase activity in a brain area called the caudate nucleus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseMonoamine oxidase activity in the caudate nucleus
    Study

    ratn: not reported in source

    stress-resistant Wistar rats chronically treated with L-DOPA
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Quantitative cytochemical assay showed that single injection of delta sleep-inducing peptide increased monoamine oxidase activity (substrates: serotonin and tryptamine) in the caudate and accumbens nuclei and glutamate dehydrogenase activity in the hippocampus of stress-resistant Wistar rats chronic…
  2. 02AnimalAnimal study (in vivo)Mechanism

    In stress-resistant Wistar rats chronically treated with L-DOPA, a single DSIP injection increased monoamine oxidase activity in the accumbens nucleus.

    In plain wordsIn rats given L-DOPA, one DSIP injection raised monoamine oxidase activity in a brain area called the accumbens nucleus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseMonoamine oxidase activity in the accumbens nucleus
    Study

    ratn: not reported in source

    stress-resistant Wistar rats chronically treated with L-DOPA
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Quantitative cytochemical assay showed that single injection of delta sleep-inducing peptide increased monoamine oxidase activity (substrates: serotonin and tryptamine) in the caudate and accumbens nuclei and glutamate dehydrogenase activity in the hippocampus of stress-resistant Wistar rats chronic…
  3. 03AnimalAnimal study (in vivo)Mechanism

    In stress-resistant Wistar rats chronically treated with L-DOPA, a single DSIP injection increased glutamate dehydrogenase activity in the hippocampus.

    In plain wordsIn rats given L-DOPA, one DSIP injection raised glutamate dehydrogenase activity in the hippocampus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseGlutamate dehydrogenase activity in the hippocampus
    Study

    ratn: not reported in source

    stress-resistant Wistar rats chronically treated with L-DOPA
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Quantitative cytochemical assay showed that single injection of delta sleep-inducing peptide increased monoamine oxidase activity (substrates: serotonin and tryptamine) in the caudate and accumbens nuclei and glutamate dehydrogenase activity in the hippocampus of stress-resistant Wistar rats chronic…
  4. 04AnimalAnimal study (in vivo)Mechanism

    In stress-resistant Wistar rats chronically treated with L-DOPA, DSIP did not change enzyme activities in the sensorimotor cortex.

    In plain wordsIn rats given L-DOPA, DSIP did not change enzyme activities in the sensorimotor cortex of the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeEnzyme activities in the sensorimotor cortex
    Study

    ratn: not reported in source

    stress-resistant Wistar rats chronically treated with L-DOPA
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Enzyme activities in the sensorimotor cortex did not change.
  5. 05AnimalAnimal study (in vivo)Mechanism

    In Wistar rats, DSIP had no effect on acetylcholine esterase activity in the brain.

    In plain wordsIn rats, DSIP did not change acetylcholine esterase activity in the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeAcetylcholine esterase activity in the brain
    Study

    ratn: not reported in source

    Wistar rats
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Delta sleep-inducing peptide had no effects on acetylcholine esterase and aminopeptidase activities in the brain of Wistar rats.
  6. 06AnimalAnimal study (in vivo)Mechanism

    In Wistar rats, DSIP had no effect on aminopeptidase activity in the brain.

    In plain wordsIn rats, DSIP did not change aminopeptidase activity in the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeAminopeptidase activity in the brain
    Study

    ratn: not reported in source

    Wistar rats
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Delta sleep-inducing peptide had no effects on acetylcholine esterase and aminopeptidase activities in the brain of Wistar rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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