Health of 227 children born after controlled ovarian stimulation for in vitro fertilization using the luteinizing hormone-releasing hormone antagonist cetrorelix.

Ludwig M, Riethmüller-Winzen H, Felberbaum RE, Olivennes F, Albano C, Devroey P, Diedrich K

Fertility and sterility1 Jan 2001Cited by 25 (Europe PMC)

PMID11163811DOI10.1016/s0015-0282(00)01632-0PepBankPUB-11163811

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

7 results from studies that gave the peptide. 7 results from people.

01HumanObservational studyEfficacy outcome
After cetrorelix ovarian stimulation, 76.2% of pregnancies resulted in live birth (179 of 234).
In plain wordsAfter cetrorelix ovarian stimulation, 76.2% of pregnancies resulted in live birth.
Peptide
Cetrorelix
Outcome
Not applicableLive birth
Study
n = 234
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Live birth
76.2%
179 of 234 pregnancies
Source sentences
Summary
Of the pregnancies, 76.2% (179 of 234) resulted in live birth
2 context sentences(design, population, supporting numbers)
Summary · context
All children born after ovarian stimulation in patients treated for infertility who were in prospective studies until March 23, 1999.
Summary · context
Controlled ovarian stimulation with cetrorelix in a multiple-dose or single/dual-dose protocol.
Report a problemFND-1116381103
02HumanObservational studySafety outcome
After cetrorelix ovarian stimulation, ectopic pregnancy occurred in 3.4% of pregnancies (8 of 231).
In plain wordsAfter cetrorelix ovarian stimulation, ectopic pregnancy occurred in 3.4% of pregnancies.
Peptide
Cetrorelix
Outcome
Not applicableEctopic pregnancy
Study
n = 231
Outcome group
Adverse events · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Ectopic pregnancy
3.4%
8 of 231
Source sentences
Summary
ectopic pregnancy occurred in 3.4% (8 of 231)
2 context sentences(design, population, supporting numbers)
Summary · context
All children born after ovarian stimulation in patients treated for infertility who were in prospective studies until March 23, 1999.
Summary · context
Controlled ovarian stimulation with cetrorelix in a multiple-dose or single/dual-dose protocol.
Report a problemFND-1116381104
03HumanObservational studyEfficacy outcome
After cetrorelix ovarian stimulation, fresh embryo transfers produced two hundred nine children.
In plain wordsAfter cetrorelix ovarian stimulation, fresh embryo transfers produced two hundred nine children.
Peptide
Cetrorelix
Outcome
Not applicableChildren born after fresh transfer
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Source sentences
Summary
Two hundred nine and 18 children were born after fresh and frozen embryo transfers, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
All children born after ovarian stimulation in patients treated for infertility who were in prospective studies until March 23, 1999.
Summary · context
Controlled ovarian stimulation with cetrorelix in a multiple-dose or single/dual-dose protocol.
Report a problemFND-1116381101
04HumanObservational studyEfficacy outcome
After cetrorelix ovarian stimulation, frozen embryo transfers produced 18 children.
In plain wordsAfter cetrorelix ovarian stimulation, frozen embryo transfers produced 18 children.
Peptide
Cetrorelix
Outcome
Not applicableChildren born after frozen transfer
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Children
18 children
frozen embryo transfer
Source sentences
Summary
Two hundred nine and 18 children were born after fresh and frozen embryo transfers, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
All children born after ovarian stimulation in patients treated for infertility who were in prospective studies until March 23, 1999.
Summary · context
Controlled ovarian stimulation with cetrorelix in a multiple-dose or single/dual-dose protocol.
Report a problemFND-1116381102
05HumanObservational studySafety outcome
After cetrorelix ovarian stimulation, investigators recorded one heterotopic pregnancy.
In plain wordsAfter cetrorelix ovarian stimulation, investigators recorded one heterotopic pregnancy.
Peptide
Cetrorelix
Outcome
Not applicableHeterotopic pregnancy
Study
n: not reported in source
Outcome group
Adverse events · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Heterotopic pregnancy
1 pregnancy
after cetrorelix ovarian stimulation
Source sentences
Summary
one heterotopic pregnancy and four induced abortions were recorded.
2 context sentences(design, population, supporting numbers)
Summary · context
All children born after ovarian stimulation in patients treated for infertility who were in prospective studies until March 23, 1999.
Summary · context
Controlled ovarian stimulation with cetrorelix in a multiple-dose or single/dual-dose protocol.
Report a problemFND-1116381105
06HumanObservational studySafety outcome
After cetrorelix ovarian stimulation, investigators recorded four induced abortions.
In plain wordsAfter cetrorelix ovarian stimulation, investigators recorded four induced abortions.
Peptide
Cetrorelix
Outcome
Not applicableInduced abortions
Study
n: not reported in source
Outcome group
Adverse events · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Induced abortions
4 abortions
after cetrorelix ovarian stimulation
Source sentences
Summary
one heterotopic pregnancy and four induced abortions were recorded.
2 context sentences(design, population, supporting numbers)
Summary · context
All children born after ovarian stimulation in patients treated for infertility who were in prospective studies until March 23, 1999.
Summary · context
Controlled ovarian stimulation with cetrorelix in a multiple-dose or single/dual-dose protocol.
Report a problemFND-1116381106
07HumanObservational studySafety outcome
After cetrorelix ovarian stimulation, the malformation rate among live births, stillbirths, and aborted fetuses was 3.1%.
In plain wordsAfter cetrorelix ovarian stimulation, the malformation rate among live births, stillbirths, and aborted fetuses was 3.1%.
Peptide
Cetrorelix
Outcome
Not applicableMalformations
Study
n: not reported in source
Outcome group
Adverse events · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Malformation rate
3.1%
live births, stillbirths, and aborted fetuses
Source sentences
Summary
The malformation rate among all live births, stillbirths, and aborted fetuses was 3.1%.
2 context sentences(design, population, supporting numbers)
Summary · context
All children born after ovarian stimulation in patients treated for infertility who were in prospective studies until March 23, 1999.
Summary · context
Controlled ovarian stimulation with cetrorelix in a multiple-dose or single/dual-dose protocol.
Report a problemFND-1116381107

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
28 Oct 2026, 02:03 UTC
Study results updated
Version 1
27 Oct 2026, 16:35 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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