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Study · Not a test of the peptide alone · 2000

5 results

Induction of early immunopotentiation to Fimbriae of Salmonella Enteritidis (SE) by administering thymulin and zinc to SE-vaccinated chicken breeders: relationship to protection.

Barbou EK, Bejjani NE, Daghir NJ, Faroon OM, Bouljihad M, Spasojevic R

The Journal of veterinary medical science1 Nov 2000Cited by 6 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymulin (serum thymic factor).

  1. 01AnimalNot a test of Thymulin (serum thymic factor) aloneAnimal study (in vivo)Efficacy outcome

    In chicken breeders, thymulin plus zinc with vaccination produced fimbrial antibodies earlier than vaccination alone.

    In plain wordsIn chickens, thymulin plus zinc with vaccination produced antibodies earlier than vaccination alone.

    Outcome
    DecreaseTime to fimbrial antibodies
    Study

    chickenn: not reported in source

    SE-vaccinated chicken breeders
    Comparator
    SE vaccination alone
    Outcome group
    Immune response · Infection

    Source sentences

    Summary
    Breeders of the first group, immunopotentiated by thymulin and zinc, were able to induce the earliest antibodies in their pooled sera at 2 weeks post the first SE-vaccination, specific to fimbriae (approximately 21 KDa) of SE.
    1 context sentence
    Summary · context
    However, the second group that was only vaccinated with the same SE-vaccine produced specific antibodies to fimbriae at 3 weeks following the second vaccination (22 weeks of age).

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

  2. 02AnimalNot a test of Thymulin (serum thymic factor) aloneAnimal study (in vivo)Efficacy outcome

    In chicken breeders, vaccination with thymulin and zinc was linked to the lowest frequency of SE-infected ceca among challenged groups.

    In plain wordsIn chickens, vaccination with thymulin and zinc was linked to the lowest frequency of infected ceca among challenged groups.

    Outcome
    DecreaseSE-infected ceca
    Study

    chickenn: not reported in source

    SE-vaccinated chicken breeders
    Comparator
    Other challenged groups
    Outcome group
    Infection and antimicrobial activity · Infection

    Measurements

    SE-infected ceca
    10%
    vaccinated thymulin and zinc group

    Source sentences

    Summary
    The presence of the earliest antibody-immunopotentiation to fimbriae of SE in breeders of the first group, administered thymulin and zinc, was associated with the lowest frequency of SE-infected ceca (10%) among the challenged groups.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

  3. 03AnimalNot a test of Thymulin (serum thymic factor) aloneAnimal study (in vivo)Efficacy outcome

    In chicken breeders, only the vaccinated thymulin and zinc group had no SE infection in cecal tonsils among challenged groups.

    In plain wordsIn chickens, only the vaccinated thymulin and zinc group had no cecal tonsil infection among challenged groups.

    Outcome
    DecreaseSE infection in cecal tonsils
    Study

    chickenn: not reported in source

    SE-vaccinated chicken breeders
    Comparator
    Other challenged groups
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    In addition, breeders of the first group were the only challenged birds resulting in absence of SE infection in their cecal tonsils.
    1 context sentence
    Summary · context
    The presence of the earliest antibody-immunopotentiation to fimbriae of SE in breeders of the first group, administered thymulin and zinc, was associated with the lowest frequency of SE-infected ceca (10%) among the challenged groups.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

  4. 04AnimalNot a test of Thymulin (serum thymic factor) aloneAnimal study (in vivo)Efficacy outcome

    In chicken breeders, both vaccinated groups, with or without thymulin and zinc, had no SE infection in oviducts.

    In plain wordsIn chickens, vaccinated groups with or without thymulin and zinc had no oviduct infection.

    Outcome
    No significant changeSE infection in oviducts
    Study

    chickenn: not reported in source

    SE-vaccinated chicken breeders
    Comparator
    Vaccination alone
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    The first group-vaccinated, immunopotentiated, and challenged, and the second group-vaccinated and challenged only resulted in breeders with absence of SE infection in their oviducts and spleens.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

  5. 05AnimalNot a test of Thymulin (serum thymic factor) aloneAnimal study (in vivo)Efficacy outcome

    In chicken breeders, both vaccinated groups, with or without thymulin and zinc, had no SE infection in spleens.

    In plain wordsIn chickens, vaccinated groups with or without thymulin and zinc had no spleen infection.

    Outcome
    No significant changeSE infection in spleens
    Study

    chickenn: not reported in source

    SE-vaccinated chicken breeders
    Comparator
    Vaccination alone
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    The first group-vaccinated, immunopotentiated, and challenged, and the second group-vaccinated and challenged only resulted in breeders with absence of SE infection in their oviducts and spleens.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:55 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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