[Characteristics of lipid peroxidation in various tissues during acute stress and its correction by pyracetam and cerebrolysin].

Deviatkina TA, Vazhnichaia EM, Lytsenko RV

Eksperimental'naia i klinicheskaia farmakologiia1 Jul 2000

PMID11022305PepBankPUB-11022305

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cerebrolysin.

01AnimalNot a test of Cerebrolysin aloneAnimal study (in vivo)Mechanism
In stressed rats, pooled nootropic agents showed a persistent CNS antioxidant effect independent of initial status.
In plain wordsIn rats under stress, pooled drugs showed a persistent brain antioxidant effect independent of initial status.
Peptide
Cerebrolysin
Outcome
Not applicableCentral nervous system antioxidant effect
Study
ratn: not reported in source
Acute immobilization stress in white male rats
Outcome group
Inflammation markers · Nervous system and cognition
Source sentences
Summary
The antioxidant effect of the nootropic agents in CNS has a permanent character, being independent of the initial status of the animal organism.
1 context sentence(design, population, supporting numbers)
Summary · context
The process of lipid peroxidation (LPO), the activity of antioxidant enzymes, and the effects of piracetam (300 mg/kg) and cerebrolysin (0.1 ml/kg) were studied in the brain, liver, thymus, spleen, and blood serum of white male rats under acute stress (immobilization) conditions.
In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.
Report a problemFND-1102230501
02AnimalNot a test of Cerebrolysin aloneAnimal study (in vivo)Mechanism
In stressed rats, piracetam and Cerebrolysin had a modulating effect on peripheral tissue lipid peroxidation.
In plain wordsIn rats under stress, piracetam and Cerebrolysin modulated lipid peroxidation in peripheral tissues.
Peptide
Cerebrolysin
Outcome
Direction not reportedPeripheral tissue lipid peroxidation
Study
ratn: not reported in source
Acute immobilization stress in white male rats
Outcome group
Inflammation markers · Whole body
Source sentences
Summary
The effect of both drugs upon the LPO level in peripheral tissues has a modulative character and can be considered as a sum of the central antistressor action and the direct influence upon the functional activity of effectors.
1 context sentence(design, population, supporting numbers)
Summary · context
The process of lipid peroxidation (LPO), the activity of antioxidant enzymes, and the effects of piracetam (300 mg/kg) and cerebrolysin (0.1 ml/kg) were studied in the brain, liver, thymus, spleen, and blood serum of white male rats under acute stress (immobilization) conditions.
In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.
Report a problemFND-1102230502

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
14 Oct 2026, 05:02 UTC
Study results updated
Version 1
14 Oct 2026, 01:46 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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