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Study · Measured the body's own peptide · 2000

1 result

Cognitive functioning and cerebrospinal fluid concentrations of neuropeptides for patients with good neurological outcomes after aneurysmal subarachnoid hemorrhage.

Uski TK, Lilja A, Säveland H, Ekman R, Sonesson B, Brandt L

Neurosurgery1 Oct 2000Cited by 12 (Europe PMC)

PMID11014419 (opens in a new tab)DOI10.1097/00006123-200010000-00002 (opens in a new tab)PepBankPUB-11014419
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In patients with good outcomes after aneurysmal subarachnoid hemorrhage, higher cerebrospinal fluid levels of the body's own delta sleep-inducing peptide correlated with cognitive impairment.

    In plain wordsIn patients after a brain bleed, higher levels of the body's own DSIP in spinal fluid were linked to cognitive impairment.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseCSF DSIP level and cognitive impairment
    Study

    n = 17

    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    However, significant correlations between cognitive impairment and elevated levels of beta-endorphins (P = 0.02), corticotropin-releasing factor (P = 0.004), and delta sleep-inducing peptide (P = 0.045) were noted.
    2 context sentences
    Summary · context
    Lumbar cerebrospinal fluid was obtained, 3 to 6 months after surgery, from 17 patients who experienced good outcomes after aneurysmal SAH.
    Summary · context
    The samples were analyzed for various neuropeptides using radioimmunoassays, and the peptide concentrations were evaluated in relation to scores on standardized neuropsychological tests.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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