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Study · Not a test of the peptide alone · 2000

2 results

Cortisol concentrations following stimulation of healthy and adrenopathic dogs with two doses of tetracosactrin.

Frank LA, DeNovo RC, Kraje AC, Oliver JW

The Journal of small animal practice1 Jul 2000Cited by 15 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cosyntropin.

  1. 01AnimalNot a test of Cosyntropin aloneAnimal study (in vivo)Activity measurement

    In healthy dogs, cortisol at 60 minutes was similar after 5 microg/kg and 250 microg intravenous tetracosactrin.

    In plain wordsIn healthy dogs, both tetracosactrin doses produced similar cortisol at 60 minutes.

    Outcome
    No significant changeCortisol at 60 minutes in healthy dogs
    Study

    dogn: not reported in source

    Healthy dogs
    Comparator
    250 microg intravenous tetracosactrin
    Outcome group
    Adrenal Function · Endocrine and hormones

    Source sentences

    Summary
    Cortisol concentrations 60 minutes after stimulation with either 5 microg/kg or 250 microg intravenous tetracosactrin were similar for both healthy dogs and dogs with hyperadrenocorticism.
    2 context sentences
    Summary · context
    A prospective study was undertaken to compare intravenous tetracosactrin at doses of 5 microg/kg and 250 microg for diagnosing hyperadrenocorticism in dogs.
    Summary · context
    Both healthy dogs and dogs with pituitary-dependent hyperadrenocorticism were evaluated with the two doses of the drug, and serum cortisol concentrations were compared at 60 minutes post-stimulation.

    In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cosyntropin.

  2. 02AnimalNot a test of Cosyntropin aloneAnimal study (in vivo)Activity measurement

    In dogs with hyperadrenocorticism, cortisol at 60 minutes was similar after 5 microg/kg and 250 microg intravenous tetracosactrin.

    In plain wordsIn dogs with hyperadrenocorticism, both tetracosactrin doses produced similar cortisol at 60 minutes.

    Outcome
    No significant changeCortisol at 60 minutes in hyperadrenocorticism
    Study

    dogn: not reported in source

    Dogs with pituitary-dependent hyperadrenocorticism
    Comparator
    250 microg intravenous tetracosactrin
    Outcome group
    Adrenal Function · Endocrine and hormones

    Source sentences

    Summary
    Cortisol concentrations 60 minutes after stimulation with either 5 microg/kg or 250 microg intravenous tetracosactrin were similar for both healthy dogs and dogs with hyperadrenocorticism.
    2 context sentences
    Summary · context
    A prospective study was undertaken to compare intravenous tetracosactrin at doses of 5 microg/kg and 250 microg for diagnosing hyperadrenocorticism in dogs.
    Summary · context
    Both healthy dogs and dogs with pituitary-dependent hyperadrenocorticism were evaluated with the two doses of the drug, and serum cortisol concentrations were compared at 60 minutes post-stimulation.

    In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cosyntropin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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