Skip to content

Study · Animal study (in vivo) · rat · 2000

3 results

[c-fos Gene expression during emotional stress in rats: blocking by delta sleep-inducing peptide].

Sudakov KV, Umriukhin PE, Koplik EV, Anokhin KV

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova1 Jun 2000Cited by 1 (Europe PMC)

PMID10955299 (opens in a new tab)PepBankPUB-10955299
Publisher pageAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats predisposed to emotional stress, DSIP inhibited c-fos expression in the paraventricular nuclei of the hypothalamus.

    In plain wordsIn rats prone to stress, DSIP reduced a stress-related gene signal in one part of the hypothalamus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Decreasec-fos expression in paraventricular nuclei of the hypothalamus
    Study

    ratn: not reported in source

    emotional stress in rats predisposed to emotional stress
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It led to an obvious inhibition of the c-fos expression in paraventricular nuclei of the hypothalamus, medial and lateral parts of the septum of rats predisposed to emotional stress.
    1 context sentence
    Summary · context
    An emotional stress induces an obvious immediate early gene c-fos expression in the brain limbic structures in the rats predisposed to emotional stress.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats predisposed to emotional stress, DSIP inhibited c-fos expression in the medial part of the septum.

    In plain wordsIn rats prone to stress, DSIP reduced a stress-related gene signal in the medial septum.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Decreasec-fos expression in medial septum
    Study

    ratn: not reported in source

    emotional stress in rats predisposed to emotional stress
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It led to an obvious inhibition of the c-fos expression in paraventricular nuclei of the hypothalamus, medial and lateral parts of the septum of rats predisposed to emotional stress.
    1 context sentence
    Summary · context
    An emotional stress induces an obvious immediate early gene c-fos expression in the brain limbic structures in the rats predisposed to emotional stress.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats predisposed to emotional stress, DSIP inhibited c-fos expression in the lateral part of the septum.

    In plain wordsIn rats prone to stress, DSIP reduced a stress-related gene signal in the lateral septum.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Decreasec-fos expression in lateral septum
    Study

    ratn: not reported in source

    emotional stress in rats predisposed to emotional stress
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It led to an obvious inhibition of the c-fos expression in paraventricular nuclei of the hypothalamus, medial and lateral parts of the septum of rats predisposed to emotional stress.
    1 context sentence
    Summary · context
    An emotional stress induces an obvious immediate early gene c-fos expression in the brain limbic structures in the rats predisposed to emotional stress.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.