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Study · Animal study (in vivo) · rat · 1999

2 results

Effect of intermittent administration of parathyroid hormone on fracture healing in ovariectomized rats.

Kim HW, Jahng JS

The Iowa orthopaedic journal1 Jan 1999Cited by 33 (Europe PMC)

PMID10847519 (opens in a new tab)PMCIDPMC1888615 (opens in a new tab)PepBankPUB-10847519
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In ovariectomized rats with tibial fractures, PTH increased callus morphometric parameters in a dose-dependent manner.

    In plain wordsIn rats with ovaries removed and broken shin bones, PTH increased callus size measures with dose.

    Peptide
    PTH 1-84 (parathyroid hormone)
    Outcome
    IncreaseFracture callus morphometric parameters
    Study

    ratn: not reported in source

    ovariectomized rats with tibial fractures
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    once a day · 30 consecutive daysAs given in this study (rat).

    Source sentences

    Summary
    Intermittent parathyroid hormone administration increased the morphometric and mechanical parameters in a dose-dependent manner.
    2 context sentences
    Summary · context
    At three months post-ovariectomy, bilateral tibial shaft fractures were induced and stabilized by intramedullary nailing with Kirschnerwires.
    Summary · context
    Saline, 17-estradiol, or recombinant human PTH(1-84) was given once a day for 30 consecutive days during fracture healing.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In ovariectomized rats with tibial fractures, PTH increased callus mechanical parameters in a dose-dependent manner.

    In plain wordsIn rats with ovaries removed and broken shin bones, PTH increased callus mechanical measures with dose.

    Peptide
    PTH 1-84 (parathyroid hormone)
    Outcome
    IncreaseFracture callus mechanical parameters
    Study

    ratn: not reported in source

    ovariectomized rats with tibial fractures
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    once a day · 30 consecutive daysAs given in this study (rat).

    Source sentences

    Summary
    Intermittent parathyroid hormone administration increased the morphometric and mechanical parameters in a dose-dependent manner.
    2 context sentences
    Summary · context
    At three months post-ovariectomy, bilateral tibial shaft fractures were induced and stabilized by intramedullary nailing with Kirschnerwires.
    Summary · context
    Saline, 17-estradiol, or recombinant human PTH(1-84) was given once a day for 30 consecutive days during fracture healing.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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