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Study · In vitro (cells) · rabbit · 2000

1 result

Differential regulation of IGF-binding proteins in rabbit costal chondrocytes by IGF-I and dexamethasone.

Koedam JA, Hoogerbrugge CM, Van Buul-Offers SC

The Journal of endocrinology1 Jun 2000Cited by 16 (Europe PMC)

PMID10828839 (opens in a new tab)DOI10.1677/joe.0.1650557 (opens in a new tab)PepBankPUB-10828839
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In rabbit costal chondrocytes, the IGF-I analog Long-R3 IGF-I induced IGFBP-5.

    In plain wordsIn rabbit cartilage cells in a dish, an IGF-I analogue increased the binding protein IGFBP-5.

    Peptide
    IGF-1 LR3
    Outcome
    IncreaseIGFBP-5 induction
    Study

    rabbitn: not reported in source

    cultured costal chondrocytes from prepubertal rabbits
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    An IGF-I analog with reduced affinity for IGFBPs, Long-R3 IGF-I, also induced IGFBP-5
    1 context sentence
    Summary · context
    We characterized the IGFBPs produced by cultured chondrocytes derived from rib cartilage of prepubertal rabbits.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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