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Study · Animal study (in vivo) · 2000

2 results

[An acute toxicity study of bromantane].

Bugaeva LI, Verovskiĭ VE, Iezhitsa IN, Spasov AA

Eksperimental'naia i klinicheskaia farmakologiia1 Jan 2000Cited by 1 (Europe PMC)

PMID10763112 (opens in a new tab)PepBankPUB-10763112
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In acute animal testing, catecholaminergic effects accounted for the therapeutic mechanism of bromantan.

    In plain wordsIn animals, catecholaminergic effects accounted for bromantan's therapeutic mechanism.

    Peptide
    Bromantane
    Outcome
    Not applicableTherapeutic mechanism
    Study

    n: not reported in source

    experimental animals
    Outcome group
    Neurotransmitters and neurotrophic factors · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was established that catecholaminergic effects account for the mechanism of therapeutic action of bromantan, while cholinergic effects determine the drug action in toxic doses.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In acute animal testing, cholinergic effects determined bromantan action at toxic doses.

    In plain wordsIn animals, cholinergic effects determined bromantan action at toxic doses.

    Peptide
    Bromantane
    Outcome
    Not applicableToxic mechanism
    Study

    n: not reported in source

    experimental animals
    Outcome group
    Neurotransmitters and neurotrophic factors · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was established that catecholaminergic effects account for the mechanism of therapeutic action of bromantan, while cholinergic effects determine the drug action in toxic doses.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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