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Study · Measured the body's own peptide · 2000

1 result

The kappa opioid receptor and dynorphin co-localize in vasopressin magnocellular neurosecretory neurons in guinea-pig hypothalamus.

Shuster SJ, Riedl M, Li X, Vulchanova L, Elde R

Neuroscience1 Jan 2000Cited by 45 (Europe PMC)

PMID10683577 (opens in a new tab)DOI10.1016/s0306-4522(99)00472-8 (opens in a new tab)PepBankPUB-10683577
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In guinea-pig hypothalamus, kappa opioid receptor positive cells were not found in the population of neurons that express the body's own oxytocin.

    In plain wordsIn guinea pigs, cells with the kappa opioid receptor were not found among the neurons that make the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    No significant changeKappa opioid receptor in oxytocin-expressing neurons
    Study

    guinea pign: not reported in source

    hypothalamic magnocellular neurosecretory neurons
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    Cells positive for either the kappa opioid receptor or both the kappa opioid receptor and preprodynorphin were restricted to the vasopressin expressing neuronal population and not found in the oxytocin expressing neuronal population.
    1 context sentence
    Summary · context
    The relationship between the cloned kappa opioid receptor, dynorphin, and the neurohypophysial hormones vasopressin and oxytocin was analysed in the guinea-pig hypothalamic magnocellular neurosecretory neurons.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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