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Study · Animal study (in vivo) · rat · 1999

5 results

[Effect of delta sleep-inducing peptide on lipid peroxidation and xanthine oxidase activity in rat tissues during cold stress].

Bondarenko TI, Miliutina NP, Shustanova TA, Mikhaleva II

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova1 Aug 1999Cited by 1 (Europe PMC)

PMID10643602 (opens in a new tab)PepBankPUB-10643602
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats, intraperitoneal exogenous DSIP decreased the amount of diene conjugates in liver and brain.

    In plain wordsIn rats, DSIP injected into the abdomen lowered a marker of fat damage (diene conjugates) in liver and brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseDiene conjugates in liver and brain
    Study

    ratn: not reported in source

    Outcome group
    Oxidative stress · Whole body
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    I. p. administration of exogenous delta-sleep-inducing peptide (DSIP) decreased the amount of diene conjugates and Schiff bases in the liver and brain in rats.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats, intraperitoneal exogenous DSIP decreased the amount of Schiff bases in liver and brain.

    In plain wordsIn rats, DSIP injected into the abdomen lowered a marker of fat damage (Schiff bases) in liver and brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseSchiff bases in liver and brain
    Study

    ratn: not reported in source

    Outcome group
    Oxidative stress · Whole body
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    I. p. administration of exogenous delta-sleep-inducing peptide (DSIP) decreased the amount of diene conjugates and Schiff bases in the liver and brain in rats.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats, intraperitoneal exogenous DSIP did not change xanthine oxidase activity.

    In plain wordsIn rats, DSIP did not change the activity of the enzyme xanthine oxidase.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeXanthine oxidase activity
    Study

    ratn: not reported in source

    Outcome group
    Oxidative stress · Whole body
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    The xanthine oxidase activity, at that, did not change.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In cold-exposed rats, preliminary DSIP diminished xanthine oxidase activity in liver and brain.

    In plain wordsIn cold-stressed rats, DSIP given beforehand lowered xanthine oxidase activity in liver and brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseXanthine oxidase activity in cold-exposed rats
    Study

    ratn: not reported in source

    Outcome group
    Oxidative stress · Whole body
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Preliminary administration of the delta-sleep-inducing peptide to cold-exposed animals diminished the xanthine oxidase activity and lipid peroxidation in the liver and brain.
  5. 05AnimalAnimal study (in vivo)Mechanism

    In cold-exposed rats, preliminary DSIP diminished lipid peroxidation in liver and brain.

    In plain wordsIn cold-stressed rats, DSIP given beforehand lowered fat damage in liver and brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseLipid peroxidation in cold-exposed rats
    Study

    ratn: not reported in source

    Outcome group
    Oxidative stress · Whole body
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Preliminary administration of the delta-sleep-inducing peptide to cold-exposed animals diminished the xanthine oxidase activity and lipid peroxidation in the liver and brain.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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