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Study · Animal study (in vivo) · mouse · 1999

1 result

Effects of neuropeptide Y deficiency on hypothalamic agouti-related protein expression and responsiveness to melanocortin analogues.

Marsh DJ, Miura GI, Yagaloff KA, Schwartz MW, Barsh GS, Palmiter RD

Brain research1 Nov 1999Cited by 95 (Europe PMC)

PMID10612698 (opens in a new tab)DOI10.1016/s0006-8993(99)01962-9 (opens in a new tab)PepBankPUB-10612698
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In NPY-deficient mice, centrally administered MTII, a melanocortin receptor agonist, produced a normal response.

    In plain wordsIn NPY-deficient mice, MTII injected into the brain had a normal effect.

    Peptide
    Melanotan II
    Outcome
    No significant changeFeeding response to central MTII in NPY-deficient mice
    Study

    mousen: not reported in source

    NPY-deficient (NPY-/-) mice
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · centralAs given in this study (mouse).

    Source sentences

    Summary
    yet exhibit a normal response to centrally administered MTII, a melanocortin receptor agonist.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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