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Study · Animal study (in vivo) · rat · 1999

2 results

Recipient preparation is critical for spermatogonial transplantation in the rat.

Ogawa T, Dobrinski I, Brinster RL

Tissue & cell1 Oct 1999Cited by 156 (Europe PMC)

PMID10612257 (opens in a new tab)DOI10.1054/tice.1999.0060 (opens in a new tab)PepBankPUB-10612257
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rat transplant recipients, leuprolide improved rat donor cell-derived spermatogenesis.

    In plain wordsIn rats receiving testis cell transplants, leuprolide improved sperm production from rat donor cells.

    Peptide
    Leuprolide
    Outcome
    IncreaseRat donor-derived spermatogenesis
    Study

    ratn: not reported in source

    Rat recipients of testis cell transplantation
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both rat and mouse donor cell-derived spermatogenesis were improved by treatment of rat recipients with leuprolide, a gonadotropin-releasing hormone agonist.
    1 context sentence
    Summary · context
    In this report, we demonstrate that rat and mouse testis cells will generate donor cell-derived spermatogenesis in recipient rat seminiferous tubules.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rat transplant recipients, leuprolide improved mouse donor cell-derived spermatogenesis.

    In plain wordsIn rats receiving testis cell transplants, leuprolide improved sperm production from mouse donor cells.

    Peptide
    Leuprolide
    Outcome
    IncreaseMouse donor-derived spermatogenesis
    Study

    ratn: not reported in source

    Rat recipients of testis cell transplantation
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both rat and mouse donor cell-derived spermatogenesis were improved by treatment of rat recipients with leuprolide, a gonadotropin-releasing hormone agonist.
    1 context sentence
    Summary · context
    In this report, we demonstrate that rat and mouse testis cells will generate donor cell-derived spermatogenesis in recipient rat seminiferous tubules.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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