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Study · Animal study (in vivo) · wistar rats and noninbred mice · 1999

4 results

[The pharmacological correction of the immune homeostasis disorders in acute dichloroethane poisoning].

Zabrodskiĭ PF, Gryzunov AV

Eksperimental'naia i klinicheskaia farmakologiia1 Sept 1999

PMID10572750 (opens in a new tab)PepBankPUB-10572750
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In poisoned rats and mice, thymogen restored reduced nonspecific anti-infectious resistance.

    In plain wordsIn rats and mice with dichloroethane poisoning, thymogen restored nonspecific resistance to infection.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseNonspecific anti-infectious resistance
    Study

    Wistar rats and noninbred micen: not reported in source

    Acute dichloroethane poisoning
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    10 mg/kg daily · 3 daysAs given in this study (Wistar rats and noninbred mice).

    Source sentences

    Summary
    Experiments on Wistar rats and noninbred mice showed that dipyroxim (10 mg/kg administered 3 times per 24 h) and thymogen (10 mg/kg daily for 3 days) restore the reduced under the effect of acute dichlorethane poisoning in a dose of 0.75 LD50 the organism's anti-infectious unspecific resistance and…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In poisoned rats and mice, thymogen restored reduced humoral immune reactions.

    In plain wordsIn rats and mice with dichloroethane poisoning, thymogen restored humoral immune reactions.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseHumoral immune reactions
    Study

    Wistar rats and noninbred micen: not reported in source

    Acute dichloroethane poisoning
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    10 mg/kg daily · 3 daysAs given in this study (Wistar rats and noninbred mice).

    Source sentences

    Summary
    Experiments on Wistar rats and noninbred mice showed that dipyroxim (10 mg/kg administered 3 times per 24 h) and thymogen (10 mg/kg daily for 3 days) restore the reduced under the effect of acute dichlorethane poisoning in a dose of 0.75 LD50 the organism's anti-infectious unspecific resistance and…
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In poisoned rats and mice, thymogen restored reduced cellular immune reactions.

    In plain wordsIn rats and mice with dichloroethane poisoning, thymogen restored cellular immune reactions.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseCellular immune reactions
    Study

    Wistar rats and noninbred micen: not reported in source

    Acute dichloroethane poisoning
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    10 mg/kg daily · 3 daysAs given in this study (Wistar rats and noninbred mice).

    Source sentences

    Summary
    Experiments on Wistar rats and noninbred mice showed that dipyroxim (10 mg/kg administered 3 times per 24 h) and thymogen (10 mg/kg daily for 3 days) restore the reduced under the effect of acute dichlorethane poisoning in a dose of 0.75 LD50 the organism's anti-infectious unspecific resistance and…

Studies that did not test the peptide alone1

In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymogen (oglufanide).

  1. 04AnimalNot a test of Thymogen (oglufanide) aloneAnimal study (in vivo)Efficacy outcome

    In poisoned rats and mice, the effects of dipyroxim and thymogen summed for the T-dependent humoral immune response.

    In plain wordsIn rats and mice, dipyroxim and thymogen had additive effects on the T-dependent humoral immune response.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseAdditive T-dependent humoral response
    Study

    Wistar rats and noninbred micen: not reported in source

    Acute dichloroethane poisoning
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Summing of the effects of the drugs under study was encountered in the case of the T-dependent humoral immune response.
    1 context sentence
    Summary · context
    Experiments on Wistar rats and noninbred mice showed that dipyroxim (10 mg/kg administered 3 times per 24 h) and thymogen (10 mg/kg daily for 3 days)

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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