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Study · Animal study (in vivo) · rat · 1999

2 results

Evidence that endogenous thymosin alpha-1 is present in the rat central nervous system.

Turrini P, Aloe L

Neurochemistry international1 Dec 1999Cited by 7 (Europe PMC)

PMID10524714 (opens in a new tab)DOI10.1016/s0197-0186(99)00084-4 (opens in a new tab)PepBankPUB-10524714
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In rats, intracerebroventricular 125I-T-alpha1 labelled neurons in the hypothalamus and septal nuclei.

    In plain wordsIn rats, labelled thymosin alpha‑1 injected into the brain ventricles was found in nerve cells of the hypothalamus and septal nuclei.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableLabelled neurons after iodinated T-alpha1
    Study

    ratn: not reported in source

    rat central nervous system
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · i.c.v.As given in this study (rat).

    Source sentences

    Summary
    Moreover, to study whether cerebral cells were receptive to T-alpha1, we injected iodinated T-alpha1 (125I-T-alpha1) i.c.v.. 125I-T-alpha1 labelled neurons were observed in the hypothalamus and septal nuclei.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In the rat central nervous system, the body's own thymosin alpha‑1 immunoreactivity was found mainly in neurons of the hippocampus and spinal cord and in small glial-like cells of specific brain regions.

    In plain wordsIn rats, the body's own thymosin alpha‑1 was found mainly in nerve cells of the hippocampus and spinal cord.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableThymosin alpha-1 immunoreactivity in rat CNS
    Study

    ratn: not reported in source

    rat central nervous system
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    T-alpha1 immunoreactivity was found mainly in neurons of the hippocampus and spinal cord and in several small cells, resembling glial cells, of specific regions of the brain.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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