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Study · Animal study (in vivo) · rat · 1999

1 result

[The biogenic amine content of rat tissues in the postresuscitation period following hemorrhagic shock and the effect of the preparation semax].

Bastrikova NA, Shestakova SV, Antonova SV, Krushinskaia IaV, Goncharenko EN, Kudriashova NIu, Novoderzhkina IS, Sokolova NA, Kozhura VL

Patologicheskaia fiziologiia i eksperimental'naia terapiia1 Jul 1999

PMID10498989 (opens in a new tab)PepBankPUB-10498989
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats resuscitated after hemorrhagic shock, intravenous semax prevented the fall in splenic serotonin on experiment day 7.

    In plain wordsIn rats after blood-loss shock, semax given into a vein prevented a drop in spleen serotonin on day 7.

    Peptide
    Semax
    Outcome
    IncreaseSplenic serotonin level on experiment day 7
    Study

    ratn: not reported in source

    Hemorrhagic shock with autoblood resuscitation
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated · intravenousAs given in this study (rat).

    Source sentences

    Summary
    Intravenous injection of semax prevented serotonin fall in the spleen on experiment day 7.
    2 context sentences
    Summary · context
    LPO products were measured in plasma and biogenic amines (serotonin, adrenalin, noradrenalin) in tissues of rats in different periods after hemorrhagic shock provoked by taking blood and maintenance of arterial pressure at the level of 40 mm Hg for 1 hour.
    Summary · context
    Resuscitation was conducted by administration of autoblood.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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