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Study · Animal study (in vivo) · mouse · 1999

4 results

[The effect of bromantane on the behavior of inbred mouse strains with different phenotypes of emotional stress reaction].

Seredenin SB, Miramedova AG, Kozlovskaia MM

Eksperimental'naia i klinicheskaia farmakologiia1 May 1999Cited by 1 (Europe PMC)

PMID10439937 (opens in a new tab)PepBankPUB-10439937
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Balb/c mice, bromantan prevented the fixed posture reaction in the open-field test.

    In plain wordsIn mice, bromantan prevented the fixed posture reaction in the open-field test.

    Peptide
    Bromantane
    Outcome
    DecreaseFixed posture reaction
    Study

    mousen: not reported in source

    Balb/c mice, open field
    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    40-50 mg/kg · oralAs given in this study (mouse).

    Source sentences

    Summary
    Per os administration of bromantan (2-[n-bromphenyl]-aminoadamantan) in doses of 40-50 mg/kg prevents the fixed posture reaction and reduces the level of defecation in Balb/c mice in the "open field" test and activates their behavior in the "elevated plus maze" test.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In Balb/c mice, bromantan reduced defecation in the open-field test.

    In plain wordsIn mice, bromantan reduced defecation in the open-field test.

    Peptide
    Bromantane
    Outcome
    DecreaseDefecation
    Study

    mousen: not reported in source

    Balb/c mice, open field
    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    40-50 mg/kg · oralAs given in this study (mouse).

    Source sentences

    Summary
    Per os administration of bromantan (2-[n-bromphenyl]-aminoadamantan) in doses of 40-50 mg/kg prevents the fixed posture reaction and reduces the level of defecation in Balb/c mice in the "open field" test and activates their behavior in the "elevated plus maze" test.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In Balb/c mice, bromantan activated behavior in the elevated plus maze.

    In plain wordsIn mice, bromantan activated behavior in the elevated plus maze.

    Peptide
    Bromantane
    Outcome
    IncreaseElevated plus maze behavior
    Study

    mousen: not reported in source

    Balb/c mice
    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    40-50 mg/kg · oralAs given in this study (mouse).

    Source sentences

    Summary
    Per os administration of bromantan (2-[n-bromphenyl]-aminoadamantan) in doses of 40-50 mg/kg prevents the fixed posture reaction and reduces the level of defecation in Balb/c mice in the "open field" test and activates their behavior in the "elevated plus maze" test.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In C57B1/c mice, bromantan increased motor activity in both behavioral tests.

    In plain wordsIn mice, bromantan increased motor activity in both behavioral tests.

    Peptide
    Bromantane
    Outcome
    IncreaseMotor activity
    Study

    mousen: not reported in source

    C57B1/c mice, open field and elevated plus maze
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    40-50 mg/kg · oralAs given in this study (mouse).

    Source sentences

    Summary
    It increases the motor activity of C57B1/c mice in both tests.
    1 context sentence
    Summary · context
    Per os administration of bromantan (2-[n-bromphenyl]-aminoadamantan) in doses of 40-50 mg/kg prevents the fixed posture reaction and reduces the level of defecation in Balb/c mice in the "open field" test and activates their behavior in the "elevated plus maze" test.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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