Localization and expression of oxytocin receptor and its messenger ribonucleic acid in peri-implantation phase human endometrium during control and clomiphene-treated cycles.

Dawood MY, Lau M, Khan-Dawood FS

American journal of obstetrics and gynecology1 Jul 1999Cited by 4 (Europe PMC)

PMID10411795DOI10.1016/s0002-9378(99)70435-7PepBankPUB-10411795

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

01HumanNot a test of Oxytocin aloneNon-randomized trialMechanism
In healthy fertile women, oxytocin receptor and its mRNA were expressed in peri-implantation endometrium in control and clomiphene-treated cycles.
In plain wordsIn healthy women, the womb lining carried the oxytocin receptor in both normal and clomiphene-treated cycles.
Peptide
Oxytocin
Outcome
Not applicableOxytocin receptor and mRNA expression in endometrium
Study
n = 5
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin receptor and its messenger ribonucleic acid were expressed in human peri-implantation phase endometrial samples from both control and clomiphene-treated cycles.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin receptor and its messenger ribonucleic acid in peri-implantation phase endometrium during control and clomiphene-treated (50 mg days 5 to 9) cycles of 5 healthy fertile women
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-1041179501
02HumanNot a test of Oxytocin aloneNon-randomized trialMechanism
In healthy fertile women, oxytocin receptor was localized mainly in epithelial cells and glands, with little or none in the stroma.
In plain wordsIn healthy women, the oxytocin receptor sat mostly in gland and surface cells of the womb lining.
Peptide
Oxytocin
Outcome
Not applicableOxytocin receptor localization in endometrium
Study
n = 5
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The receptor was localized predominantly in the epithelial cells and glands, with little or none detected in the stroma.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin receptor and its messenger ribonucleic acid in peri-implantation phase endometrium during control and clomiphene-treated (50 mg days 5 to 9) cycles of 5 healthy fertile women
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-1041179502
03HumanNot a test of Oxytocin aloneNon-randomized trialMechanism
In healthy fertile women, oxytocin receptor protein abundance was significantly lower in clomiphene-treated cycles than in control cycles.
In plain wordsIn healthy women, the womb lining held less oxytocin receptor in clomiphene-treated cycles than in normal cycles.
Peptide
Oxytocin
Outcome
DecreaseOxytocin receptor protein abundance, clomiphene versus control cycles
Study
n = 5
Comparator
Control cycles
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin receptor protein was separated out as a single 70-kd band by Western blot analysis; its relative abundance was significantly reduced during clomiphene-treated cycles.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin receptor and its messenger ribonucleic acid in peri-implantation phase endometrium during control and clomiphene-treated (50 mg days 5 to 9) cycles of 5 healthy fertile women
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-1041179503
04HumanNot a test of Oxytocin aloneNon-randomized trialMechanism
In healthy fertile women, oxytocin receptor mRNA expression was greater in control cycles than in clomiphene-treated cycles.
In plain wordsIn healthy women, oxytocin receptor messenger RNA was higher in normal cycles than in clomiphene-treated cycles.
Peptide
Oxytocin
Outcome
DecreaseOxytocin receptor mRNA expression, clomiphene versus control cycles
Study
n = 5
Comparator
Control cycles
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
The messenger ribonucleic acid was detected in all endometrium during control and clomiphene-treated cycles, with greater expression during control cycles.
1 context sentence(design, population, supporting numbers)
Summary · context
Oxytocin receptor and its messenger ribonucleic acid in peri-implantation phase endometrium during control and clomiphene-treated (50 mg days 5 to 9) cycles of 5 healthy fertile women
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-1041179504

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:51 UTC
First added · source update from Europe PMC

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