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Study · Animal study (in vivo) · rat · 1999

4 results

Metabolic features of the adaptive effect of delta-sleep inducing peptide and piracetam under hyperoxic conditions.

Lysenko AV, Alperovich DV, Uskova NI, Mendzheritsky AM

Biochemistry. Biokhimiia1 Jun 1999

PMID10395980 (opens in a new tab)PepBankPUB-10395980
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats, DSIP produced differential changes in the neurotransmitter amino acids GABA, glutamate and aspartate in sensomotor cortex membranes.

    In plain wordsIn rats, DSIP changed levels of the brain messenger amino acids GABA, glutamate and aspartate in different ways.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    MixedNeurotransmitter amino acids (GABA, glutamate, aspartate) in neuronal membranes
    Study

    ratn: not reported in source

    rats under hyperbaric oxygenation
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    12 microgram/100 g body weight · intraperitoneal · single injectionAs given in this study (rat).

    Source sentences

    Summary
    differential changes in neurotransmitter amino acids (GABA, glutamate, aspartate)
    2 context sentences
    Summary · context
    Adaptive effects of delta-sleep inducing peptide (DSIP, 12 microgram/100 g body weight, single intraperitoneal injection)
    Summary · context
    Under hyperbaric oxygenation (0.3 MPa for 2 h)
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats, DSIP modulated transport ATPase activity in sensomotor cortex neuronal membranes.

    In plain wordsIn rats, DSIP modulated the activity of a transport enzyme in brain cell membranes.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Direction not reportedTransport ATPase activity in neuronal membranes
    Study

    ratn: not reported in source

    rats under hyperbaric oxygenation
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    12 microgram/100 g body weight · intraperitoneal · single injectionAs given in this study (rat).

    Source sentences

    Summary
    modulation of transport ATPase activity
    2 context sentences
    Summary · context
    Adaptive effects of delta-sleep inducing peptide (DSIP, 12 microgram/100 g body weight, single intraperitoneal injection)
    Summary · context
    Under hyperbaric oxygenation (0.3 MPa for 2 h)
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats, DSIP decreased accumulation of lipid peroxidation products in myelin, synaptic and mitochondrial membranes of the sensomotor cortex.

    In plain wordsIn rats, DSIP reduced build-up of fat-damage products in brain cell membranes.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseLipid peroxidation products in neuronal membranes
    Study

    ratn: not reported in source

    rats under hyperbaric oxygenation
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    12 microgram/100 g body weight · intraperitoneal · single injectionAs given in this study (rat).

    Source sentences

    Summary
    decreased accumulation of lipid peroxidation products (conjugated dienes, malonic dialdehyde, Schiff bases) in various fractions of neuronal membranes (myelin, synaptic and mitochondrial membranes) in the sensomotor cortex of rat brain
    2 context sentences
    Summary · context
    Adaptive effects of delta-sleep inducing peptide (DSIP, 12 microgram/100 g body weight, single intraperitoneal injection)
    Summary · context
    Under hyperbaric oxygenation (0.3 MPa for 2 h)

Studies that did not test the peptide alone1

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 04AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Mechanism

    In rats under hyperbaric oxygenation, the combination of DSIP and piracetam enhanced the protective effect of each compound.

    In plain wordsIn rats under high-pressure oxygen, DSIP together with piracetam gave more protection than either compound did alone.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseProtective effect of DSIP plus piracetam under hyperbaric oxygenation
    Study

    ratn: not reported in source

    rats under hyperbaric oxygenation
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    Under hyperbaric oxygenation (0.3 MPa for 2 h), the combination of DSIP and piracetam enhanced the protective effect of each compound.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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