In acute ischemic stroke, a retrospective analysis found that Semax shifted the balance toward anti-inflammatory mediators (interleukin-10, tumor necrosis factor-alpha) over inflammatory ones (interleukin-8, C-reactive protein).
In plain wordsIn people with acute stroke, Semax was linked to a shift toward anti-inflammatory signals and away from inflammatory signals.
- Peptide
- Semax
- Outcome
- MixedBalance of anti-inflammatory and pro-inflammatory mediators
- Study
n: not reported in source
- Outcome group
- Inflammation markers · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
A retrospective comparative clinicoimmunobiochemical analysis provided objective data on the molecular level on activating influence of Semax on antiinflammatory postischemic reactions in the brain.
2 context sentences(design, population, supporting numbers)
Shifting neuromediatory balance toward a prevalence of the antiinflammatory agents (interleukin-10, tumor necrosis factor-alpha) over the factors maintaining the inflammation (interleukin-8, C-reactive protein).
A clinical trial was performed of immunobiochemical mechanisms of neuroprotective properties of Semax in acute period of ischemic stroke.