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Study · In vitro (cells) · 1999

3 results

In vitro synaptotrophic effects of Cerebrolysin in NT2N cells.

Mallory M, Honer W, Hsu L, Johnson R, Rockenstein E, Masliah E

Acta neuropathologica1 May 1999Cited by 22 (Europe PMC)

PMID10334480 (opens in a new tab)DOI10.1007/s004010051012 (opens in a new tab)PepBankPUB-10334480
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In NT2N cells, Cerebrolysin augmented synaptic-associated protein expression compared with its absence.

    In plain wordsIn cells, Cerebrolysin increased synaptic protein expression compared with cells without Cerebrolysin.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseSynaptic-associated protein expression magnitude
    Study

    humann: not reported in source

    NT2N neurons differentiated from NTera 2 cells
    Comparator
    Absence of Cerebrolysin
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    and Cerebrolysin treatment of NT2N cells resulted in an augmented and earlier expression of synaptic-associated proteins.
    1 context sentence
    Summary · context
    We studied the patterns of expression of synaptic proteins during differentiation of human teratocarcinoma cell line NTera 2 (NT2) in the presence or absence of Cerebrolysin.
  2. 02LabIn vitro (cells)Mechanism

    In NT2N cells, Cerebrolysin induced earlier synaptic-associated protein expression compared with its absence.

    In plain wordsIn cells, synaptic proteins appeared earlier with Cerebrolysin than without it.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseSynaptic-associated protein expression timing
    Study

    humann: not reported in source

    NT2N neurons differentiated from NTera 2 cells
    Comparator
    Absence of Cerebrolysin
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    and Cerebrolysin treatment of NT2N cells resulted in an augmented and earlier expression of synaptic-associated proteins.
    1 context sentence
    Summary · context
    We studied the patterns of expression of synaptic proteins during differentiation of human teratocarcinoma cell line NTera 2 (NT2) in the presence or absence of Cerebrolysin.
  3. 03LabIn vitro (cells)Mechanism

    In NT2N cells, increased synaptic protein expression with Cerebrolysin coincided with increased APP695 relative to APP770/751.

    In plain wordsIn cells, increased synaptic proteins with Cerebrolysin accompanied increased APP695 relative to other APP forms.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseAPP695 relative to APP770/751
    Study

    humann: not reported in source

    NT2N neurons differentiated from NTera 2 cells
    Comparator
    Absence of Cerebrolysin
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    This increased synaptic protein expression coincided with an increase in APP695 over APP770/751.
    2 context sentences
    Summary · context
    and Cerebrolysin treatment of NT2N cells resulted in an augmented and earlier expression of synaptic-associated proteins.
    Summary · context
    We studied the patterns of expression of synaptic proteins during differentiation of human teratocarcinoma cell line NTera 2 (NT2) in the presence or absence of Cerebrolysin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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