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Study · Measured the body's own peptide · 1999

2 results

Endocrine and behavioral traits in low-avoidance Sprague-Dawley rats.

Uvnäs-Moberg K, Björkstrand E, Salmi P, Johansson C, Astrand M, Ahlenius S

Regulatory peptides1 Mar 1999Cited by 11 (Europe PMC)

PMID10235637 (opens in a new tab)DOI10.1016/s0167-0115(99)00014-2 (opens in a new tab)PepBankPUB-10235637
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In Sprague-Dawley rats, plasma oxytocin was significantly lower in the low-avoidance Stock B than in Stock A.

    In plain wordsIn rats, the body's own oxytocin level in blood was lower in the stock that learned avoidance poorly than in the other stock.

    Peptide
    Oxytocin
    Outcome
    DecreasePlasma oxytocin in low-performing Stock B versus Stock A
    Study

    ratn: not reported in source

    Sprague-Dawley rats, Stock A and Stock B
    Comparator
    Stock A
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    plasma gastrin and oxytocin were significantly lowered and a strong tendency for a decrease also in plasma CCK.
    2 context sentences
    Summary · context
    In the present series of experiments, we have examined the endocrine profile of two stable colonies of Sprague-Dawley rats, here labeled Stock A, and Stock B, differing markedly in their ability to acquire a conditioned avoidance response.
    Summary · context
    The experiments were concluded by taking blood samples for later analysis of plasma glucose and plasma levels of the following hormones: insulin, gastrin, CCK, glucagon, somatostatin, oxytocin and corticosterone.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In Sprague-Dawley rats, plasma oxytocin correlated positively with avoidance performance.

    In plain wordsIn rats, higher natural oxytocin levels in blood were linked to better avoidance performance.

    Peptide
    Oxytocin
    Outcome
    IncreaseCorrelation of plasma oxytocin with avoidance performance
    Study

    ratn: not reported in source

    Sprague-Dawley rats, Stock A and Stock B
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Taking total variability in avoidance performance into account, there was a statistically significant positive correlation between plasma oxytocin, as well as gastrin, levels and avoidance performance.
    2 context sentences
    Summary · context
    In the present series of experiments, we have examined the endocrine profile of two stable colonies of Sprague-Dawley rats, here labeled Stock A, and Stock B, differing markedly in their ability to acquire a conditioned avoidance response.
    Summary · context
    The experiments were concluded by taking blood samples for later analysis of plasma glucose and plasma levels of the following hormones: insulin, gastrin, CCK, glucagon, somatostatin, oxytocin and corticosterone.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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