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Study · Measured the body's own peptide · 1998

1 result

Neuroendocrine and hypothermic effects of 5-HT1A receptor stimulation with ipsapirone in healthy men: a placebo-controlled study.

Cleare AJ, Forsling M, Bond AJ

International clinical psychopharmacology1 Jan 1998Cited by 19 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In healthy men, oral ipsapirone stimulated release of the body's own oxytocin, less robustly and with more baseline variation than other pituitary hormones.

    In plain wordsIn healthy men, the drug ipsapirone raised the body's own oxytocin, but less strongly and less consistently than other hormones.

    Peptide
    Oxytocin
    Outcome
    IncreasePlasma oxytocin release after ipsapirone
    Study

    n = 12

    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Release of the posterior pituitary hormone oxytocin was also stimulated, but less robustly and with more baseline variation.
    1 context sentence
    Summary · context
    We used the 5-HT1A receptor partial agonist ipsapirone (20 mg) as an oral serotonergic challenge drug in a random-order, double-blind placebo-controlled study of 12 healthy men.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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