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Study · Measured the body's own peptide · 1998

1 result

Sensory stimulation (acupuncture) increases the release of vasoactive intestinal polypeptide in the saliva of xerostomia sufferers.

Dawidson I, Angmar-Månsson B, Blom M, Theodorsson E, Lundeberg T

Neuropeptides1 Dec 1998Cited by 40 (Europe PMC)

PMID9920452 (opens in a new tab)DOI10.1016/s0143-4179(98)90083-x (opens in a new tab)PepBankPUB-09920452
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In patients with xerostomia, the concentration of VIP in saliva rose significantly after a course of 24 acupuncture sessions compared with before treatment.

    In plain wordsIn people with dry mouth, acupuncture raised the body's own VIP in saliva compared with before treatment.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreaseSalivary VIP concentration after acupuncture
    Study

    n = 17

    Comparator
    Before acupuncture
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    The results showed that there was a significant increase of the concentration of VIP after the AP as compared to the measurements made before the start of the treatment (p<0.05).
    2 context sentences
    Summary · context
    Seventeen patients out of 65 were chosen due to their ability to produce enough saliva for the radio immunoassay (RIA) analyses to be conducted prior to the start of AP.
    Summary · context
    VIP-like immunoreactivity (VIP-LI) was measured in the chewing stimulated saliva of these patients before and after the whole AP (24 sessions of 30 min each).

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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