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Study · Animal study (in vivo) · 1998

1 result

Feeding effects of hypothalamic injection of melanocortin 4 receptor ligands.

Giraudo SQ, Billington CJ, Levine AS

Brain research1 Nov 1998Cited by 144 (Europe PMC)

PMID9853124 (opens in a new tab)DOI10.1016/s0006-8993(98)00837-3 (opens in a new tab)PepBankPUB-09853124
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    MT II, an MC4-R agonist, had extremely potent effects on feeding when injected into the paraventricular nucleus.

    In plain wordsIn an animal study, MT II injected into a brain area called the PVN had very strong effects on feeding.

    Peptide
    Melanotan II
    Outcome
    Direction not reportedFeeding effect of MT II injected in the paraventricular nucleus
    Study

    n: not reported in source

    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · paraventricular nucleus injectionAs given in this study.

    Source sentences

    Summary
    We found that MT II and SHU9119 have extremely potent effects on feeding when injected in the paraventricular nucleus (PVN), a site where MC4-R gene expression is very high.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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