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Study · In vitro (cells) · 1997

2 results

Relationship between GHRP-6 and TPA in the regulation of growth hormone secretion by human pituitary somatotrophinomas.

Liu Q, Lei T, Adams EF, Buchfedlder M, Fahlbusch R

Journal of Tongji Medical University = Tong ji yi ke da xue xue bao1 Jan 1997Cited by 5 (Europe PMC)

PMID9812762 (opens in a new tab)DOI10.1007/bf02888286 (opens in a new tab)PepBankPUB-09812762
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In human somatotrophinoma cultures, GHRP‑6 stimulated GH secretion.

    In plain wordsIn cells from human pituitary tumors, GHRP‑6 stimulated growth hormone release.

    Peptide
    GHRP-6
    Outcome
    IncreaseGH secretion
    Study

    humann: not reported in source

    pituitary somatotrophinoma cultures
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results showed that the working mechanisms of GHRP-6 and TPA are not identical, although they all can stimulate GH secretion in human pituitary somatotrophinomas.
    1 context sentence
    Summary · context
    We used cell cultures of human pituitary somatotrophinomas to investigate the relation between GHRP-6 and TPA on membrane phosphatidylinositol (PI) turnover and GH secretion.
  2. 02LabIn vitro (cells)Mechanism

    In human somatotrophinoma cultures, GHRP‑6 and TPA had different mechanisms of action.

    In plain wordsIn cells from human pituitary tumors, GHRP‑6 and TPA acted through different mechanisms.

    Peptide
    GHRP-6
    Outcome
    Not applicableMechanism relative to TPA
    Study

    humann: not reported in source

    pituitary somatotrophinoma cultures
    Comparator
    TPA
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results showed that the working mechanisms of GHRP-6 and TPA are not identical, although they all can stimulate GH secretion in human pituitary somatotrophinomas.
    1 context sentence
    Summary · context
    We used cell cultures of human pituitary somatotrophinomas to investigate the relation between GHRP-6 and TPA on membrane phosphatidylinositol (PI) turnover and GH secretion.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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