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Study · Animal study (in vivo) · rat · 1998

1 result

[Shifts in the constant potential in the structures of the rat brain in focal ischemia and systemic hypoxia].

Bures J, Koroleva VI, Korolev OS, Mares V

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova1 Jul 1998Cited by 1 (Europe PMC)

PMID9778808 (opens in a new tab)PepBankPUB-09778808
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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with carbon monoxide hypoxia, Cerebrolysin prevented severe hippocampal injury with granulomas seen in untreated rats.

    In plain wordsIn rats with carbon monoxide hypoxia, Cerebrolysin prevented severe hippocampal injury seen in untreated rats.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseSevere hippocampal injury
    Study

    ratn: not reported in source

    Carbon monoxide hypoxia
    Comparator
    Rats not treated with cerebrolysin
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    2.5 ml/kg daily · 10 daysAs given in this study (rat).

    Source sentences

    Summary
    Cerebrolysin (2.5 ml/kg daily, during 10 days) prevented from severe hippocampal injury (formation of granulomas) usually seen in the left hemisphere of rats not treated with cerebrolysin.
    1 context sentence
    Summary · context
    The role of spreading depression (SD) in the development of ischemic brain damage in rats was studied in two models: focal cortical ischemia provoked by a photothrombotic occlusion of the middle cerebral artery (MCA) and systemic hypoxia induced by breathing with 0.8% carbon monoxide (CO).

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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