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Study · In vitro (cells) · 1998

1 result

Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I.

Akagi Y, Liu W, Zebrowski B, Xie K, Ellis LM

Cancer research1 Sept 1998Cited by 115 (Europe PMC)

PMID9731515 (opens in a new tab)PepBankPUB-09731515
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In HT29 colon cancer cells, des-(1-3)-IGF-I had effects on VEGF mRNA expression similar to IGF-I.

    In plain wordsIn cells, des-(1-3)-IGF-I had effects on VEGF mRNA expression similar to IGF-I.

    Peptide
    IGF-1 DES (des(1-3)IGF-I)
    Outcome
    No significant changeVEGF mRNA expression
    Study

    n: not reported in source

    HT29 human colon cancer cells
    Comparator
    IGF-I
    Outcome group
    Receptor activity and mechanism · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Treating cells with des-(1-3)-IGF-I (an active derivative of IGF-I that does not bind to binding proteins) had effects on VEGF mRNA expression that were similar to those of IGF-I.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:52 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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