In a patient with chronic hepatitis B treated with thymosin alpha1, an S gene mutant of hepatitis B virus emerged during therapy.
In plain wordsIn one patient with hepatitis B treated with thymosin alpha‑1, a changed form of the virus appeared during treatment.
- Peptide
- Thymosin alpha-1
- Outcome
- Not applicableEmergence of hepatitis B virus S gene mutant during therapy
- Study
n = 1
- Outcome group
- Antiviral activity · Infection
- Studied dose
- Dose not stated
Source sentences
In summary, an S gene mutant was identified in an HBsAg-seronegative patient.
2 context sentences(design, population, supporting numbers)
The emergence of an S gene mutant during thymosin alpha1 treatment suggests that enhanced host immunity against HBsAg may play a role in its antiviral activity.
The presence of a hepatitis B virus S gene mutant was investigated in a patient being treated with thymosin alpha1.