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Study · Animal study (in vivo) · rat · 1998

2 results

Differential responses of estrogen target tissues in rats including bone to clomiphene, enclomiphene, and zuclomiphene.

Turner RT, Evans GL, Sluka JP, Adrian MD, Bryant HU, Turner CH, Sato M

Endocrinology1 Sept 1998Cited by 19 (Europe PMC)

PMID9724022 (opens in a new tab)DOI10.1210/endo.139.9.6177 (opens in a new tab)PepBankPUB-09724022
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In ovariectomized rats, enclomiphene had dose-dependent effects on most measurements similar to clomiphene.

    In plain wordsIn rats with removed ovaries, enclomiphene had dose-dependent effects on most measurements similar to clomiphene.

    Peptide
    Enclomiphene
    Outcome
    Direction not reportedDose-dependent tissue measurements
    Study

    ratn: not reported in source

    ovariectomized female rats with cancellous osteopenia
    Comparator
    clomiphene
    Outcome group
    Receptor activity and mechanism · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In contrast, ENC had dose-dependent effects on most measurements similar to CLO and decreased the uterotrophic effects of ZUC.
    1 context sentence
    Summary · context
    These studies were performed in 7-month-old female rats with moderate cancellous osteopenia that was established by ovariectomizing rats 1 month before initiating treatment.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In ovariectomized rats, enclomiphene decreased the uterotrophic effects of zuclomiphene.

    In plain wordsIn rats with removed ovaries, enclomiphene reduced the effects of zuclomiphene on uterine growth.

    Peptide
    Enclomiphene
    Outcome
    DecreaseZuclomiphene uterotrophic effects
    Study

    ratn: not reported in source

    ovariectomized female rats with cancellous osteopenia
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In contrast, ENC had dose-dependent effects on most measurements similar to CLO and decreased the uterotrophic effects of ZUC.
    1 context sentence
    Summary · context
    These studies were performed in 7-month-old female rats with moderate cancellous osteopenia that was established by ovariectomizing rats 1 month before initiating treatment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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