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Study · Animal study (in vivo) · rat · 1998

4 results

Can Cerebrolysin influence chronic deterioration of spatial learning and memory?

Valousková V, Francis-Turner L

Journal of neural transmission. Supplementum1 Jan 1998Cited by 3 (Europe PMC)

PMID9700670 (opens in a new tab)DOI10.1007/978-3-7091-6467-9_30 (opens in a new tab)PepBankPUB-09700670
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with chronic CNS lesions, Cerebrolysin restored learning capability.

    In plain wordsIn rats with chronic brain lesions, Cerebrolysin restored learning ability.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseLearning capability
    Study

    ratn: not reported in source

    CNS lesion
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The present study shows that Cerebrolysin restored learning capability of the lesioned rats.
    1 context sentence
    Summary · context
    The drug was applied 4 months after lesioning the rat's CNS.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In lesioned rats, Cerebrolysin improved spatial memory compared with untreated lesioned controls.

    In plain wordsIn lesioned rats, Cerebrolysin improved spatial memory compared with untreated lesioned rats.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseSpatial memory versus lesioned controls
    Study

    ratn: not reported in source

    CNS lesion
    Comparator
    Lesioned untreated controls
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although their spatial memory was improved in comparison to lesion untreated controls, it did not reach the level of intact controls.
    1 context sentence
    Summary · context
    The drug was applied 4 months after lesioning the rat's CNS.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In lesioned rats, spatial memory after Cerebrolysin remained below the level of intact controls.

    In plain wordsIn lesioned rats, spatial memory after Cerebrolysin remained below that of intact rats.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseSpatial memory versus intact controls
    Study

    ratn: not reported in source

    CNS lesion
    Comparator
    Intact controls
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although their spatial memory was improved in comparison to lesion untreated controls, it did not reach the level of intact controls.
    1 context sentence
    Summary · context
    The drug was applied 4 months after lesioning the rat's CNS.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In lesioned rats, the Cerebrolysin effect was more pronounced at 1.25 ml/kg than at 2.5 ml/kg.

    In plain wordsIn lesioned rats, Cerebrolysin had a greater effect at 1.25 ml/kg than at 2.5 ml/kg.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseDose comparison of cognitive effect
    Study

    ratn: not reported in source

    CNS lesion
    Comparator
    2.5 ml/kg b. w. Cerebrolysin
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    1.25 ml/kg b. w.As given in this study (rat).

    Source sentences

    Summary
    The effect was more pronounced after the application of 1.25 ml/kg b. w. of Cerebrolysin than after the application of 2.5 ml/kg b. w.
    1 context sentence
    Summary · context
    The drug was applied 4 months after lesioning the rat's CNS.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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