Skip to content

Study · Measured the body's own peptide · 1998

3 results

Effect of residual endogenous insulin secretion on the abnormal oxytocin response to hypoglycaemia in insulin-dependent diabetics.

Volpi R, Chiodera P, Capretti L, Caffarri G, Giuliani N, Caiazza A, Coiro V

Journal of internal medicine1 Jul 1998Cited by 3 (Europe PMC)

PMID9698023 (opens in a new tab)DOI10.1046/j.1365-2796.1998.00313.x (opens in a new tab)PepBankPUB-09698023
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In men with insulin-dependent diabetes and in normal men, basal concentrations of the body's own oxytocin were similar.

    In plain wordsIn men with and without type 1 diabetes, basal levels of the body's own oxytocin were similar.

    Peptide
    Oxytocin
    Outcome
    No significant changeBasal oxytocin concentration
    Study

    n = 31

    Comparator
    Normal subjects
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    The basal concentrations of OT were similar in all groups.
    2 context sentences
    Summary · context
    Case-control study: the OT response to insulin-induced hypoglycaemia was measured in normal and diabetic patients with or without residual endogenous insulin secretion.
    Summary · context
    Ten normal male subjects, 10 C-peptide positive (CpP) and 11 C-peptide negative (CpN) male diabetic patients.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In men with insulin-dependent diabetes, the rise of the body's own oxytocin during insulin-induced hypoglycaemia was significantly higher than in normal men.

    In plain wordsIn men with type 1 diabetes, the body's own oxytocin rose more during low blood sugar than in healthy men.

    Peptide
    Oxytocin
    Outcome
    IncreaseHypoglycaemia-induced oxytocin rise in diabetic versus normal subjects
    Study

    n = 31

    Comparator
    Normal subjects
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Hypoglycaemia-induced OT rise was significantly higher in the two diabetic groups than in the normal group.
    2 context sentences
    Summary · context
    Case-control study: the OT response to insulin-induced hypoglycaemia was measured in normal and diabetic patients with or without residual endogenous insulin secretion.
    Summary · context
    Ten normal male subjects, 10 C-peptide positive (CpP) and 11 C-peptide negative (CpN) male diabetic patients.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In men with insulin-dependent diabetes, C-peptide negative patients had significantly higher increments of the body's own oxytocin during hypoglycaemia than C-peptide positive patients.

    In plain wordsIn men with type 1 diabetes, those without residual insulin production had a larger rise in the body's own oxytocin during low blood sugar.

    Peptide
    Oxytocin
    Outcome
    IncreaseHypoglycaemia-induced oxytocin rise in C-peptide negative versus positive diabetics
    Study

    n = 21

    Comparator
    C-peptide positive diabetic patients
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    However, CpN patients showed significantly higher OT increments than CpP subjects.
    2 context sentences
    Summary · context
    Case-control study: the OT response to insulin-induced hypoglycaemia was measured in normal and diabetic patients with or without residual endogenous insulin secretion.
    Summary · context
    Ten normal male subjects, 10 C-peptide positive (CpP) and 11 C-peptide negative (CpN) male diabetic patients.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.