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Study · Measured the body's own peptide · 1998

2 results

Gender-dependent dissociation between oxytocin but not ACTH, cortisol or TSH responses to m-chlorophenylpiperazine in healthy subjects.

Bagdy G, Arato M

Psychopharmacology1 Apr 1998Cited by 9 (Europe PMC)

PMID9600579 (opens in a new tab)DOI10.1007/s002130050576 (opens in a new tab)PepBankPUB-09600579
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In healthy men, oral m-CPP did not significantly change plasma levels of the body's own oxytocin; the oxytocin response was seen in women only.

    In plain wordsIn healthy men, the drug m-CPP did not clearly change the body's own oxytocin levels; only women showed a response.

    Peptide
    Oxytocin
    Outcome
    No significant changePlasma oxytocin response to m-CPP in men
    Study

    n = 7

    Comparator
    Placebo
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Significant plasma oxytocin responses were found in female subjects only; thus this effect of m-CPP was statistically significantly gender dependent.
    3 context sentences
    Summary · context
    This study examined whether m-CPP had any effect on plasma oxytocin, TSH and aldosterone concentration in healthy volunteers using a double-blind, placebo-controlled crossover design.
    Summary · context
    Male subjects (n=7) received placebo, 0.25 and 0.5 mg/kg oral m-CPP.
    Summary · context
    In female subjects (n=5), the effects of placebo and 0.25 mg/kg m-CPP were studied.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialOther

    In healthy women, oral m-CPP (0.25 mg/kg) increased plasma levels of the body's own oxytocin versus placebo.

    In plain wordsIn healthy women, the drug m-CPP raised the body's own oxytocin levels compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreasePlasma oxytocin response to m-CPP in women
    Study

    n = 5

    Comparator
    Placebo
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Significant plasma oxytocin responses were found in female subjects only; thus this effect of m-CPP was statistically significantly gender dependent.
    3 context sentences
    Summary · context
    This study examined whether m-CPP had any effect on plasma oxytocin, TSH and aldosterone concentration in healthy volunteers using a double-blind, placebo-controlled crossover design.
    Summary · context
    Male subjects (n=7) received placebo, 0.25 and 0.5 mg/kg oral m-CPP.
    Summary · context
    In female subjects (n=5), the effects of placebo and 0.25 mg/kg m-CPP were studied.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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