In obese postmenopausal women receiving diet and exercise, fat mass decreased by 6.3 +/- 1.8 kg with GH, with decreases in all groups.
In plain wordsIn obese postmenopausal women receiving diet and exercise, fat mass decreased with GH, but fat loss occurred in all groups.
- Peptide
- HGH (somatotropin)
- Outcome
- DecreaseFat mass
- Study
n: not reported in source
- Outcome group
- Body composition · Metabolic and weight
- Studied dose
- 0.025 mg/kg BW.day · self-injection · 12 weeksAs given in this study (human).
Measurements
- Fat mass decrease
- 6.3 kg
- GH group, SD 1.8 kg; fat mass also decreased in all groups
Source sentences
Fat mass significantly decreased in all groups, with the largest losses observed in GH and GH plus IGF-I groups (6.3 +/- 1.8 and 8.4 +/- 2.8 kg, respectively).
3 context sentences(design, population, supporting numbers)
To determine the effects of GH and insulin-like growth factor I (IGF-I) administration, diet, and exercise on weight loss, body composition, basal metabolic rate (BMR), muscle strength, and psychological status, 33 moderately obese postmenopausal women (67.1 +/- 5.2 yr) participated in a 12-week ran…
Participants were placed on a diet that provided 500 Cal/day less than that needed for weight maintenance, and they walked 3 days and strength trained 2 days each week.
Subjects also self-injected GH (0.025 mg/kg BW.day), IGF-I (0.015 mg/kg BW.day), a combination of these doses of GH and IGF-I, or placebo (P).