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Study · In vitro (cells) · 1998

2 results

Acromegaly and Cushing's syndrome due to ectopic production of GHRH and ACTH by a thymic carcinoid tumour: in vitro responses to GHRH and GHRP-6.

Jansson JO, Svensson J, Bengtsson BA, Frohman LA, Ahlman H, Wängberg B, Nilsson O, Nilsson M

Clinical endocrinology1 Feb 1998Cited by 38 (Europe PMC)

PMID9579239 (opens in a new tab)DOI10.1046/j.1365-2265.1998.3471213.x (opens in a new tab)PepBankPUB-09579239
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In primary cultures from a hormone-producing thymic carcinoid, GHRP‑6 elicited calcium influx.

    In plain wordsIn lab tests, GHRP‑6 elicited calcium entry into cells from a hormone-producing thymic carcinoid tumor.

    Peptide
    GHRP-6
    Outcome
    IncreaseCalcium influx
    Study

    humann: not reported in source

    primary cultures of thymic carcinoid tumor cells
    Outcome group
    Receptor activity and mechanism · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In primary culture, cells from this tumour displayed calcium influx in response to GHRH or GH releasing peptide-6 (GHRP-6)
  2. 02LabIn vitro (cells)Activity measurement

    In cells from another carcinoid lacking GHRH, ACTH and NPY production, GHRP‑6 did not elicit calcium influx.

    In plain wordsIn lab tests, GHRP‑6 did not elicit calcium entry into cells from another carcinoid without production of the listed hormones.

    Peptide
    GHRP-6
    Outcome
    No significant changeCalcium influx
    Study

    humann: not reported in source

    cells from another carcinoid not producing GHRH, ACTH or NPY
    Outcome group
    Receptor activity and mechanism · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In primary culture, cells from this tumour displayed calcium influx in response to GHRH or GH releasing peptide-6 (GHRP-6), while there were not such responses by cells from another carcinoid not producing GHRH, ACTH or NPY.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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