In immature rat pituitary cells, about one-third of POMC-responsive cells also increased intracellular calcium in response to the GHRP‑6 identification challenge.
In plain wordsIn cells from immature rat pituitary glands, about one-third of POMC-responsive cells also showed a calcium increase with GHRP‑6.
- Peptide
- GHRP-6
- Outcome
- IncreaseCalcium response in POMC-responsive cells
- Study
ratn: not reported in source
isolated pituitary cells from immature female rats- Outcome group
- Receptor activity and mechanism · Endocrine and hormones
Source sentences
About one-third of the cells responsive to these peptides also showed a [Ca2+]i increase in response to growth hormone-releasing peptide-6 (GHRP-6)
2 context sentences(design, population, supporting numbers)
To further characterize these two biological responses, the present study compared changes in the intracellular free calcium concentration ([Ca2+]i) in response to POMC1-76 and POMC1-26 in isolated pituitary cells from 14-day-old female rats.
Calcium (Ca2+) responses were also used as a guide to determine whether the responsive cells belong to the lactosomatotroph lineage.
In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.