In rat kidney brush border membranes, a DSIP containing an L-isoaspartyl residue inhibited GTPgammaS-induced methylation of substrates with molecular weights above 36 kDa.
In plain wordsIn rat kidney membrane tests, a DSIP variant blocked part of a protein methylation reaction.
- Outcome
- DecreaseGTPgammaS-induced methylation of substrates above 36 kDa
- Study
ratn: not reported in source
kidney cortex brush border membranes- Outcome group
- Receptor activity and mechanism · Kidney and urinary
Source sentences
while a delta-sleep-inducing peptide containing an L-isoaspartyl residue inhibited that of substrates with molecular weights above 36 kDa
1 context sentence(design, population, supporting numbers)
The increase in carboxyl methylation induced by guanosine 5',3-O-(thio)triphosphate (GTPgammaS) in brush border membranes from rat kidney cortex was studied, and the methyltransferase activities affected by this nucleotide analog were identified.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).