In healthy men, melatonin 5 mg for 4 days abolished the nocturnal increase of oxytocin seen in the placebo study.
In plain wordsIn healthy men, four days of melatonin removed the night-time rise of the body's own oxytocin seen with placebo.
- Peptide
- Oxytocin
- Outcome
- DecreaseNocturnal oxytocin increase after melatonin
- Study
n = 10
- Comparator
- Placebo
- Outcome group
- Pituitary hormones · Endocrine and hormones
Source sentences
the nocturnal increase of oxytocin was absent.
2 context sentences(design, population, supporting numbers)
Vasopressin and oxytocin levels were found to increase during the night in the control study, but the period of the nocturnal increase in vasopressin concentrations was reduced after the administration of melatonin and the nocturnal increase of oxytocin was absent.
Double-blind controlled clinical study.SubjectsTen adult healthy male volunteers, aged 21-33 years, were studied on two occasions: once after the administration of melatonin 5 mg orally for 4 days at 1700 hours and once after the administration of placebo, at similar times.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.