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Study · Measured the body's own peptide · 1998

3 results

Real-time relationships between intraluteal and plasma concentrations of endothelin, oxytocin, and progesterone during prostaglandin F2alpha-induced luteolysis in the cow.

Ohtani M, Kobayashi S, Miyamoto A, Hayashi K, Fukui Y

Biology of reproduction1 Jan 1998Cited by 80 (Europe PMC)

PMID9472929 (opens in a new tab)DOI10.1095/biolreprod58.1.103 (opens in a new tab)PepBankPUB-09472929
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In cows with microdialysis in the corpus luteum, intraluteal oxytocin release reached 950% within 4 h after PGF2alpha injection.

    In plain wordsIn cows, the body's own oxytocin in the corpus luteum rose sharply within 4 hours after a luteolysis-inducing injection.

    Peptide
    Oxytocin
    Outcome
    IncreaseIntraluteal oxytocin release peak
    Study

    cown = 11

    Microdialysis in the corpus luteum during PGF2alpha-induced luteolysis
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Measurements

    Intraluteal oxytocin release peak
    950%
    within 4 h after PGF2alpha

    Source sentences

    Summary
    Intraluteal release of ET-1 increased (p < 0.05) to 160% within 4 h after PGF2alpha injection, when an enormous OT release (to 950%) occurred, which reached a plateau of 250% after 20 h that persisted until 72 h.
    2 context sentences
    Summary · context
    In the second study, a microdialysis system (MDS) was surgically implanted into the CL of 11 cows in the midluteal phase.
    Summary · context
    A PGF2alpha analogue (cloprostenol; 500 microg) was then injected (designated as 0 h) i.m. to induce luteolysis.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In cows, intraluteal oxytocin release stayed at a plateau of 250% from 20 h until 72 h after PGF2alpha injection.

    In plain wordsIn cows, the body's own oxytocin in the corpus luteum stayed raised for up to 72 hours after the injection.

    Peptide
    Oxytocin
    Outcome
    IncreaseIntraluteal oxytocin release plateau
    Study

    cown = 11

    Microdialysis in the corpus luteum during PGF2alpha-induced luteolysis
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Measurements

    Intraluteal oxytocin plateau
    250%
    20 h to 72 h after PGF2alpha

    Source sentences

    Summary
    Intraluteal release of ET-1 increased (p < 0.05) to 160% within 4 h after PGF2alpha injection, when an enormous OT release (to 950%) occurred, which reached a plateau of 250% after 20 h that persisted until 72 h.
    2 context sentences
    Summary · context
    In the second study, a microdialysis system (MDS) was surgically implanted into the CL of 11 cows in the midluteal phase.
    Summary · context
    A PGF2alpha analogue (cloprostenol; 500 microg) was then injected (designated as 0 h) i.m. to induce luteolysis.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In cows, the acute oxytocin release almost dropped to baseline at 2 h after PGF2alpha injection, when ET-1 release into the ovarian vein began to rise.

    In plain wordsIn cows, the short burst of the body's own oxytocin nearly returned to baseline about 2 hours after the injection.

    Peptide
    Oxytocin
    Outcome
    DecreaseAcute oxytocin release at 2 h
    Study

    cown = 11

    Microdialysis in the corpus luteum during PGF2alpha-induced luteolysis
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    ET-1 release into the ovarian vein began to increase at 2 h after PGF2alpha injection, when the acute OT release almost dropped to the baseline.
    2 context sentences
    Summary · context
    In the second study, a microdialysis system (MDS) was surgically implanted into the CL of 11 cows in the midluteal phase.
    Summary · context
    A PGF2alpha analogue (cloprostenol; 500 microg) was then injected (designated as 0 h) i.m. to induce luteolysis.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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