In orthostatic hypotension, standing time was 13.2 +/- 3.9 min after octreotide versus 3.5 +/- 7 min without treatment (P = .0034).
In plain wordsIn orthostatic hypotension, octreotide increased standing time compared with no treatment.
- Peptide
- Octreotide
- Outcome
- IncreaseStanding time
- Study
n: not reported in source
- Comparator
- No treatment
- Outcome group
- Blood pressure · Cardiovascular
- Studied dose
- 1.0 microgram/kgAs given in this study (human).
Measurements
- Standing time
- 13.2 min
- after 1.0 microgram/kg octreotide
- Standing time
- 3.5 min
- no treatment
- P value versus no treatment
- 0.0034 P
- octreotide versus no treatment
Source sentences
In the absence of treatment, standing time was 3.5 +/- 7 min; 1 h after 10 mg midodrine, 8.4 +/- 2.7 min (P = .11); after 1.0 microgram/kg octreotide, 13.2 +/- 3.9 min (P = .0034 vs. no treatment);
2 context sentences(design, population, supporting numbers)
The purpose of this study was to compare two treatments for orthostatic hypotension, midodrine (an alpha adrenergic agonist), and octreotide (an SRIH analogue) to each other and to combination therapy.
Sixteen patients participated.