In 66 patients with venous stasis ulcers, iontophoresis of CGRP plus VIP with standard treatment significantly improved healing compared with standard treatment plus placebo iontophoresis.
In plain wordsIn people with venous leg ulcers, CGRP and VIP given by iontophoresis improved healing more than placebo iontophoresis. Both groups also had standard treatment.
- Outcome
- IncreaseVenous ulcer healing
- Study
n = 66
- Comparator
- Standard treatment plus placebo iontophoresis
- Outcome group
- Wound healing · Skin and wound
Source sentences
there were significant improvements of the healing process in the group treated with calcitonin gene-related peptide and vasoactive intestinal polypeptide when compared with placebo iontophoresis
2 context sentences(design, population, supporting numbers)
Two randomized groups of patients were compared, one receiving standard treatment plus iontophoresis of calcitonin gene-related peptide and vasoactive intestinal polypeptide, and the other receiving standard treatment plus placebo iontophoresis.
Calcitonin gene-related peptide and vasoactive intestinal polypeptide were administered locally by iontophoresis for 20 min three times weekly for 12 weeks.
In this study, Vasoactive intestinal peptide (VIP, aviptadil) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Vasoactive intestinal peptide (VIP, aviptadil).