Regulation of bovine cervical secretion of prostaglandins and synthesis of cyclooxygenase by oxytocin.

Shemesh M, Dombrovski L, Gurevich M, Shore LS, Fuchs AR, Fields MJ

Reproduction, fertility, and development1 Jan 1997Cited by 30 (Europe PMC)

PMID9418982DOI10.1071/r96114PepBankPUB-09418982

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

01LabEx vivo tissueMechanism
In bovine cervical tissue in vitro, oxytocin stimulated induction of cyclooxygenase II.
In plain wordsIn cow cervical tissue in the lab, oxytocin increased the cyclooxygenase II enzyme.
Peptide
Oxytocin
Outcome
IncreaseCyclooxygenase II induction
Study
cown = 7
bovine cervical external os tissue explants
Outcome group
Inflammation markers · Reproductive and sexual health
Studied dose
10 ng mL[-1] · 3 hAs given in this study (cow).
Measurements
Cyclooxygenase II induction
79%
OT-stimulated
Source sentences
Summary
OT stimulated the induction of cyclooxygenase II (79+/-10%; n = 7, P < 0.05).
1 context sentence(design, population, supporting numbers)
Summary · context
It was therefore determined whether OT can stimulate prostaglandin synthesis or induce cyclooxygenase expression in cervical external os segments obtained from pre-oestrous-oestrous cows.
Report a problemFND-0941898203
02LabEx vivo tissueMechanism
In bovine cervical external os tissue from pre-oestrous-oestrous cows, oxytocin stimulated basal prostaglandin E2 production in vitro.
In plain wordsIn cow cervical tissue in the lab, oxytocin raised production of prostaglandin E2.
Peptide
Oxytocin
Outcome
IncreaseBasal PGE2 production
Study
cown = 6
bovine cervical external os tissue explants
Outcome group
Inflammation markers · Reproductive and sexual health
Studied dose
10 ng mL[-1] · 6 hAs given in this study (cow).
Measurements
PGE2
7.79 ng 100 mg[-1]
OT-stimulated, external os segments
Source sentences
Summary
OT stimulated basal PGE2 (7.79+/-1.22 ng 100 mg[-1], mean+/-s.e.m.; n = 6) in external os segments from pre-oestrous-oestrous cows (P < 0.03)
1 context sentence(design, population, supporting numbers)
Summary · context
It was therefore determined whether OT can stimulate prostaglandin synthesis or induce cyclooxygenase expression in cervical external os segments obtained from pre-oestrous-oestrous cows.
Report a problemFND-0941898201
03LabEx vivo tissueMechanism
In bovine cervical tissue in vitro, oxytocin had no effect on basal prostaglandin F2alpha production, which was minimal.
In plain wordsIn cow cervical tissue in the lab, oxytocin did not change production of prostaglandin F2alpha.
Peptide
Oxytocin
Outcome
No significant changeBasal PGF2alpha production
Study
cown: not reported in source
bovine cervical external os tissue explants
Outcome group
Inflammation markers · Reproductive and sexual health
Studied dose
10 ng mL[-1] · 6 hAs given in this study (cow).
Source sentences
Summary
Basal prostaglandin F2alpha (PGF2alpha) production was minimal (<1 ng 100 mg[-1]) and OT had no effect on its production.
1 context sentence(design, population, supporting numbers)
Summary · context
It was therefore determined whether OT can stimulate prostaglandin synthesis or induce cyclooxygenase expression in cervical external os segments obtained from pre-oestrous-oestrous cows.
Report a problemFND-0941898202

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:52 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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