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Study · Animal study (in vivo) · calf · 1997

4 results

No desensitization of the growth hormone (GH) response between GH-releasing peptide-2 and GH-releasing factor in calves.

Roh SG, He ML, Matsunaga N, Hidaka S, Hidari H

Journal of animal science1 Oct 1997Cited by 9 (Europe PMC)

PMID9331880 (opens in a new tab)DOI10.2527/1997.75102749x (opens in a new tab)PepBankPUB-09331880
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In calves, continuous GHRP‑2 exposure attenuated the GH secretion caused by a GHRP‑2 bolus.

    In plain wordsIn calves, a steady GHRP‑2 infusion weakened the growth hormone release caused by a later GHRP‑2 injection.

    Peptide
    GHRP-2
    Outcome
    DecreaseGH response to GHRP-2 bolus during GHRP-2 infusion
    Study

    calfn = 4

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    12.5 micrograms.kgBW-1.h-1 infusion; 12.5 micrograms/kg BW bolus · 180 minAs given in this study (calf).

    Source sentences

    Summary
    Continuous exposure to GHRP-2 attenuated the GH secretion caused by a GHRP-2 bolus.
    1 context sentence
    Summary · context
    The GHRP-2 (12.5 micrograms.kgBW-1.h-1) or GH-releasing factor (GRF; .125 microgram.kgBW-1.h-1) were infused for 180 min into four calves, each followed by either GHRP-2 (12.5 micrograms/kg BW) or GRF (.125 microgram/kg BW) injection after 60 min.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In calves, the attenuation of the GH response to repeated GHRP‑2 injections was maintained until 4 h.

    In plain wordsIn calves, the weaker growth hormone response to repeated GHRP‑2 injections lasted until the 4-hour interval.

    Peptide
    GHRP-2
    Outcome
    DecreaseAttenuation of GH response to repeated GHRP-2 injections
    Study

    calfn: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    12.5 micrograms/kg BW · up to 4 h between injectionsAs given in this study (calf).

    Source sentences

    Summary
    Attenuation of the GH response caused by GHRP-2 was maintained until 4 h.
    1 context sentence
    Summary · context
    In an additional experiment, two repetitive injections of GHRP-2 (12.5 micrograms/kg BW) at 1-, 2-, 3-, or 4-h intervals were administered.

Studies that did not test the peptide alone2

In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-2.

  1. 03AnimalNot a test of GHRP-2 aloneAnimal study (in vivo)Activity measurement

    In calves, continuous GHRP‑2 infusion did not attenuate the GH secretion caused by a GRF bolus.

    In plain wordsIn calves, a steady GHRP‑2 infusion did not weaken the growth hormone release caused by a GRF injection.

    Peptide
    GHRP-2
    Outcome
    No significant changeGH response to GRF bolus during GHRP-2 infusion
    Study

    calfn = 4

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    The continuous infusion of GHRP-2 did not attenuate the GH secretion caused by a GRF bolus
    1 context sentence
    Summary · context
    The GHRP-2 (12.5 micrograms.kgBW-1.h-1) or GH-releasing factor (GRF; .125 microgram.kgBW-1.h-1) were infused for 180 min into four calves, each followed by either GHRP-2 (12.5 micrograms/kg BW) or GRF (.125 microgram/kg BW) injection after 60 min.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  2. 04AnimalNot a test of GHRP-2 aloneAnimal study (in vivo)Activity measurement

    In calves, continuous GRF infusion did not attenuate the GH secretion caused by a GHRP‑2 bolus.

    In plain wordsIn calves, a steady GRF infusion did not weaken the growth hormone release caused by a GHRP‑2 injection.

    Peptide
    GHRP-2
    Outcome
    No significant changeGH response to GHRP-2 bolus during GRF infusion
    Study

    calfn = 4

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    and vice versa.
    1 context sentence
    Summary · context
    The GHRP-2 (12.5 micrograms.kgBW-1.h-1) or GH-releasing factor (GRF; .125 microgram.kgBW-1.h-1) were infused for 180 min into four calves, each followed by either GHRP-2 (12.5 micrograms/kg BW) or GRF (.125 microgram/kg BW) injection after 60 min.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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