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Study · Measured the body's own peptide · 1996

1 result

Studies on the sites and mechanisms of 5-HT1A receptor-mediated in vivo actions.

Bagdy G

Acta physiologica Hungarica1 Jan 1996Cited by 6 (Europe PMC)

PMID9328612 (opens in a new tab)PepBankPUB-09328612
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats, surgical lesions of the paraventricular nucleus markedly attenuated the oxytocin response to ipsapirone.

    In plain wordsIn rats, damage to a brain area called the PVN strongly reduced the body's own oxytocin response to a serotonin-receptor drug.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin response to ipsapirone after PVN lesion
    Study

    ratn: not reported in source

    rats with paraventricular nucleus lesions given ipsapirone
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Surgical lesions of the PVN completely blocked ACTH and corticosterone and markedly attenuated oxytocin but not prolactin responses to ipsapirone, providing evidence for a crucial role of the PVN in these responses.
    1 context sentence
    Summary · context
    In the first study the possible role of the hypothalamic paraventricular nucleus (PVN) in 5-HT1A receptor agonist-induced neuroendocrine responses was tested.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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