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Study · Ex vivo tissue · 1997

3 results

[The effect of thymogen on the heart in ischemia and reperfusion].

Filippova OV, Reznikov KM, Alabovskił VV, Khamburov VV, Vinokurov AA

Eksperimental'naia i klinicheskaia farmakologiia1 May 1997

PMID9324392 (opens in a new tab)PepBankPUB-09324392
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueEfficacy outcome

    In isolated hearts, thymogen produced greater cardioprotection than dalargin.

    In plain wordsIn lab tests, thymogen protected isolated hearts more than dalargin.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseCardioprotection versus dalargin
    Study

    n: not reported in source

    isolated heart
    Comparator
    dalargin
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Its cardioprotective effect was higher than that of dalargin and verapamil.
    1 context sentence
    Summary · context
    The anti-ischemic properties of thymogen were studied on an isolated heart model.
  2. 02LabEx vivo tissueEfficacy outcome

    In isolated hearts, thymogen produced greater cardioprotection than verapamil.

    In plain wordsIn lab tests, thymogen protected isolated hearts more than verapamil.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseCardioprotection versus verapamil
    Study

    n: not reported in source

    isolated heart
    Comparator
    verapamil
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Its cardioprotective effect was higher than that of dalargin and verapamil.
    1 context sentence
    Summary · context
    The anti-ischemic properties of thymogen were studied on an isolated heart model.
  3. 03LabEx vivo tissueMechanism

    In isolated hearts, thymogen's anti-ischemic action did not involve opiate receptors or blockade of calcium entry into cardiomyocytes.

    In plain wordsIn lab tests, thymogen's heart protection did not involve opiate receptors or blocked calcium entry into heart cells.

    Peptide
    Thymogen (oglufanide)
    Outcome
    Not applicableAnti-ischemic mechanism
    Study

    n: not reported in source

    isolated heart
    Outcome group
    Receptor activity and mechanism · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The mechanism of the thymogen anti-ischemic action is realized without the participation of the opiate receptors and blockade of calcium entrance into the cardiomyocytes.
    1 context sentence
    Summary · context
    The anti-ischemic properties of thymogen were studied on an isolated heart model.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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