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Study · Measured the body's own peptide · 1997

2 results

Abnormal plasma oxytocin and beta-endorphin levels in alcoholics after short and long term abstinence.

Marchesi C, Chiodera P, Brusamonti E, Volpi R, Coiro V

Progress in neuro-psychopharmacology & biological psychiatry1 Jul 1997Cited by 28 (Europe PMC)

PMID9278951 (opens in a new tab)DOI10.1016/s0278-5846(97)00080-8 (opens in a new tab)PepBankPUB-09278951
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In male alcoholics after alcohol withdrawal, the body's own plasma oxytocin levels were higher than in normal controls at all examined time points.

    In plain wordsIn male alcoholics after withdrawal, the body's own oxytocin levels in blood were higher than in healthy controls.

    Peptide
    Oxytocin
    Outcome
    IncreasePlasma oxytocin level versus controls
    Study

    n = 22

    Comparator
    Normal controls
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    At all examined time points, plasma OX and ES, but not VP, levels were significantly higher in alcoholics than in controls.
    1 context sentence
    Summary · context
    Plasma oxytocin (OX), vasopressin (VP), estrone (ES) and beta-endorphin (beta-end) levels were measured in 13 male non-chirrotic alcoholics, at 1, 4, 7, 15 and 28 days after alcohol withdrawal and only once in 9 sex- and age-matched normal controls.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In male alcoholics, plasma estrone levels were positively related to the body's own plasma oxytocin levels.

    In plain wordsIn male alcoholics, higher estrone levels were linked to higher levels of the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    Not applicableAssociation between estrone and oxytocin levels
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    A positive relationship was found between ES and OX levels suggesting that elevated estrogens levels in chronic alcoholics might exert a stimulatory effect on OX.
    1 context sentence
    Summary · context
    Plasma oxytocin (OX), vasopressin (VP), estrone (ES) and beta-endorphin (beta-end) levels were measured in 13 male non-chirrotic alcoholics, at 1, 4, 7, 15 and 28 days after alcohol withdrawal and only once in 9 sex- and age-matched normal controls.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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