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Study · Not a test of the peptide alone · 1997

4 results

[A clinical and experimental validation of the use of Stimuloss in patients with chronic generalized periodontitis].

Fedosenko TD, Vladimirova LG, Ivasenko IN

Stomatologiia1 Jan 1997

PMID9245001 (opens in a new tab)PepBankPUB-09245001
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymogen (oglufanide).

  1. 01HumanNot a test of Thymogen (oglufanide) aloneNon-randomized trialEfficacy outcome

    In patients with periodontitis, Stimulos compositions, particularly those containing immunostimulants, were associated with disappearance of inflammation.

    In plain wordsIn patients with periodontitis, inflammation disappeared after Stimulos treatment, particularly with compositions containing immunostimulants.

    Peptide
    Thymogen (oglufanide)
    Outcome
    DecreaseInflammation resolution
    Study

    n = 66

    Outcome group
    Inflammation markers · Immune and inflammation

    Source sentences

    Summary
    Trials of Stimulos in 66 patients with chronic generalized periodontitis demonstrated its high efficacy, particularly of the compositions containing immunostimulants: inflammation disappeared and the height of alveolar osseous tissue increased, as did bone compactness.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  2. 02HumanNot a test of Thymogen (oglufanide) aloneNon-randomized trialEfficacy outcome

    In patients with periodontitis, Stimulos compositions, particularly those containing immunostimulants, increased alveolar bone height.

    In plain wordsIn patients with periodontitis, Stimulos compositions increased alveolar bone height, particularly those containing immunostimulants.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseAlveolar bone height
    Study

    n = 66

    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    Trials of Stimulos in 66 patients with chronic generalized periodontitis demonstrated its high efficacy, particularly of the compositions containing immunostimulants: inflammation disappeared and the height of alveolar osseous tissue increased, as did bone compactness.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  3. 03HumanNot a test of Thymogen (oglufanide) aloneNon-randomized trialEfficacy outcome

    In patients with periodontitis, Stimulos compositions, particularly those containing immunostimulants, increased bone compactness.

    In plain wordsIn patients with periodontitis, Stimulos compositions increased bone compactness, particularly those containing immunostimulants.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseBone compactness
    Study

    n = 66

    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    Trials of Stimulos in 66 patients with chronic generalized periodontitis demonstrated its high efficacy, particularly of the compositions containing immunostimulants: inflammation disappeared and the height of alveolar osseous tissue increased, as did bone compactness.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  4. 04LabNot a test of Thymogen (oglufanide) aloneIn vitro (cells)Efficacy outcome

    In human osteogenic tissue culture, adding chlorohexidine and thymogen did not decrease the composition's osteoinductive properties.

    In plain wordsIn cells, adding chlorohexidine and thymogen did not decrease the composition's bone-forming properties.

    Peptide
    Thymogen (oglufanide)
    Outcome
    No significant changeOsteoinductive properties
    Study

    humann: not reported in source

    osteogenic tissue culture
    Comparator
    Composition without added chlorohexidine and thymogen
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    Addition of chlorohexidine and thymogen to the composition in order to increase its antibacterial activity did not decrease the osteoinductive properties of the drug.
    1 context sentence
    Summary · context
    The pharmacological effect of hydroxyapatite and a composition based on it in the form of Stimulos sponge has been studied in human osteogenic tissue culture.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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