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Study · Ex vivo tissue · rat · 1997

2 results

Inhibition by TGF-beta 1 of the in vitro thymulin-stimulated proliferation of gonocytes from fetal rat testes.

Prépin J, Le Vigouroux P

Reproduction, nutrition, development1 Jan 1997Cited by 3 (Europe PMC)

PMID9178360 (opens in a new tab)DOI10.1051/rnd:19970207 (opens in a new tab)PepBankPUB-09178360
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueMechanism

    In fetal rat testis explants, thymulin stimulated male germ cell proliferation.

    In plain wordsIn lab tests, thymulin increased male germ cell growth in fetal rat testis tissue.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseFetal gonocyte proliferation
    Study

    ratn: not reported in source

    testis explants from 13.5 gestation day rat fetuses
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A thymus hormone, thymulin, stimulated the proliferation of fetal male germ cells in explants of testes from 13.5 gestation day rat fetuses.

Studies that did not test the peptide alone1

In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymulin (serum thymic factor).

  1. 02LabNot a test of Thymulin (serum thymic factor) aloneEx vivo tissueMechanism

    In fetal rat testis cultures, TGF-beta 1 blocked the germ cell response to thymulin.

    In plain wordsIn lab tests, TGF-beta 1 blocked the response of fetal rat germ cells to thymulin.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    DecreaseGonocyte response with TGF-beta 1
    Study

    ratn: not reported in source

    testis explants from 13.5 gestation day rat fetuses
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Adding TGF-beta 1 to the culture medium blocked the response of the fetal male rat germ cells to thymulin.
    1 context sentence
    Summary · context
    A thymus hormone, thymulin, stimulated the proliferation of fetal male germ cells in explants of testes from 13.5 gestation day rat fetuses.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:55 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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