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Study · Animal study (in vivo) · rat · 1996

3 results

[A rotational syndrome induced by administration of the delta sleep-inducing peptide into the reticular portion of the rat substantia nigra].

Shandra AA, Godlevskiĭ LS, Vast'ianov RS, Zaporozhchenko MB, Ibragim M, Brusentsov AI, Oleĭnik AA

Fiziologicheskii zhurnal imeni I.M. Sechenova1 Oct 1996

PMID9162398 (opens in a new tab)PepBankPUB-09162398
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, unilateral intranigral delta-sleep-induced peptide evoked contralateral rotation.

    In plain wordsIn rats, delta sleep-inducing peptide injected into one side of the substantia nigra caused rotation toward the opposite side.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseContralateral rotation after intranigral administration
    Study

    ratn: not reported in source

    Outcome group
    Locomotor and behavioral activity · Nervous system and cognition
    Studied dose
    Dose not stated · intranigralAs given in this study (rat).

    Source sentences

    Summary
    Unilateral intranigral administration of a delta-sleep-induced peptide (DSIP) evoked a contralateral rotation.

Studies that did not test the peptide alone2

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 02AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Mechanism

    In rats, naloxone prevented the development of the rotation caused by intranigral delta-sleep-induced peptide.

    In plain wordsIn rats, naloxone prevented the rotation that delta sleep-inducing peptide caused.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseNaloxone effect on DSIP-induced rotation
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Naloxon prevented development of the effect whereas haloperidol administration enhanced the DSIP cataleptogenic effect.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 03AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Mechanism

    In rats, haloperidol enhanced the cataleptogenic effect of intranigral delta-sleep-induced peptide.

    In plain wordsIn rats, haloperidol strengthened the catalepsy effect that delta sleep-inducing peptide caused.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseHaloperidol effect on DSIP cataleptogenic effect
    Study

    ratn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    haloperidol administration enhanced the DSIP cataleptogenic effect.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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